ReviewAnnals of the New York Academy of Sciences2010
New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression.
Review in Annals of the New York Academy of Sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 63 citations in OpenAlex.
- The Role of S100A8/A9 in Autoimmune Eye Diseases: From Pathogenesis to Targeted Therapy.Investigative ophthalmology & visual science · 2026Review
- Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies.Nature communications · 2023Article
- Molecular Peptide Grafting as a Tool to Create Novel Protein Therapeutics.Molecules (Basel, Switzerland) · 2023Review
- Inflammatory Bowel Disease: Clinical Diagnosis and Pharmaceutical Management.Medical research archives · 2023Article
- Inflammatory Bowel Disease: Clinical Diagnosis and Surgical Treatment-Overview.Medicina (Kaunas, Lithuania) · 2022Review
- Anti-Proliferative Effect ofMolecules (Basel, Switzerland) · 2020Article
- Pro-inflammatory dopamine-2 receptor-specific T cells in paediatric movement and psychiatric disorders.Clinical & translational immunology · 2020Article
- Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer.British journal of cancer · 2019Article
- Cellular miR-2909 RNomics governs the genes that ensure immune checkpoint regulation.Molecular and cellular biochemistry · 2019Article
- A Novel Derivative of (-)mycousnine Produced by the Endophytic FungusFrontiers in microbiology · 2017Article
- Targeted suppression of autoreactive CD8Scientific reports · 2016Article
- Macrophage-T cell interactions mediate neuropathic pain through the glucocorticoid-induced tumor necrosis factor ligand system.The Journal of biological chemistry · 2015Article
- Soluble co-signaling molecules predict long-term graft outcome in kidney-transplanted patients.PloS one · 2014Article
- Natural killer T (NKT) cells in autoimmune hepatitis.Current opinion in immunology · 2013Review
- The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.Advances in pharmacology (San Diego, Calif.) · 2013Review
- The human condition: an immunological perspective.Nature immunology · 2011Article
- Persistence of cell-mediated immunity three decades after vaccination with the live vaccine strain of Francisella tularensis.European journal of immunology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
T cell-directed therapies have become mainstays in the management of various autoimmune diseases and organ transplantation. The understanding of T cell biology has expanded greatly since the development of most agents currently in use. Here we discuss important recent discoveries pertaining to T helper cell differentiation, lineage commitment, and function. Within this context, we examine existing T cell-directed therapies, including new agents being evaluated in clinical and preclinical studies. We also use recent findings to speculate on novel targets.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.