ArticleJournal of abnormal child psychology2010
Personality mediation of genetic effects on Attention-Deficit/Hyperactivity Disorder.
Article in Journal of abnormal child psychology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Role of dopamine receptors in ADHD: a systematic meta-analysis.Molecular neurobiology · 2012Pooled it
- Negative Parenting Mediates the Longitudinal Association between Parental Internalizing Symptoms and Child Oppositional Symptoms.Child psychiatry and human development · 2025Trial
- Incremental Validity of ADHD Dimensions in the Predictions of Emotional Symptoms, Conduct Problems, and Peer Problems in Adolescents Based on Parent, Teacher, and Self-Ratings.Pediatric reports · 2024Article
- Mental health in Canadian children and adolescents during COVID-19 pandemic: the role of personality and, coping and stress responses.Frontiers in psychology · 2023Article
- Longitudinal Temperament Pathways to ADHD Between Childhood and Adolescence.Research on child and adolescent psychopathology · 2022Article
- Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traits.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016Article
- Personality profiles in adults with attention deficit hyperactivity disorder (ADHD).BMC psychiatry · 2016Article
- Personality Traits Elucidate Sex Differences in Attention-Deficit/Hyperactivity Disorder Comorbidity During Early Childhood.Journal of psychopathology and behavioral assessment · 2014Article
- An examination of the specificity of motivation and executive functioning in ADHD symptom-clusters in adolescence.Journal of pediatric psychology · 2013Article
- Adult attention deficit hyperactivity disorder symptoms and five-factor model traits in a clinical sample: a structural equation modeling approach.The Journal of nervous and mental disease · 2013Article
- Personality dimensions as common and broadband-specific features for internalizing and externalizing disorders.Journal of abnormal child psychology · 2013Article
- Child dopamine active transporter 1 genotype and parenting: evidence for evocative gene-environment correlations.Development and psychopathology · 2013Article
- Diversity in pathways to common childhood disruptive behavior disorders.Journal of abnormal child psychology · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Personality traits may be viable candidates for mediators of the relationship between genetic risk and ADHD. Participants were 578 children (331 boys; 320 children with ADHD) between the ages of six and 18. Parents and teachers completed a comprehensive, multi-stage diagnostic procedure to assess ADHD and comorbid disorders. Mother completed the California Q-Sort to assess child Big Five personality traits. Children provided buccal samples of DNA which were assayed for selected markers on DRD4, DAT1, and ADRA2A. An additive genetic risk composite was associated with ADHD symptoms and maladaptive personality traits; maladaptive personality traits were associated with ADHD symptoms. Low conscientiousness and high neuroticism partially mediated the relationship between genetic risk and ADHD symptoms. Mediation effects for conscientiousness were specific to inattentive symptoms; effects for neuroticism generalized to all disruptive behaviors. High neuroticism and low conscientiousness may be useful as early markers for children at risk for ADHD.
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