ArticleNeurocritical care2010
Infectious vasculopathy of intracranial large- and medium-sized vessels in neurological intensive care unit: a clinico-radiological study.
Article in Neurocritical care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 42 citations in OpenAlex.
- Syphilis and cerebral stroke: a case report and systematic review.Neurological research and practice · 2026Article
- Cerebral vasculitis as a severe complication of acute infectious meningoencephalitis-a case series of five different pathogens.Wiener medizinische Wochenschrift (1946) · 2025Article
- Post-infectious central nervous system vasculitides in adults: an underdiagnosed and treatable disease part II. Neuroimaging of selected etiologies : Part II. Neuroimaging of selected etiologies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Article
- Cross-Sectional Retrospective Study to Identify Clinical and Radiographic Features Associated With VZV Reactivation in Cryptogenic Stroke Patients With CSF Testing.The Neurohospitalist · 2022Article
- Cerebrovascular Complications After Adult-Onset Varicella-Zoster Virus Encephalitis in the Central Nervous System: A Literature Review.Neuropsychiatric disease and treatment · 2022Review
- Ruptured cerebral pseudoaneurysm in an adolescent as an early onset of COVID-19 infection: case report.Acta neurochirurgica · 2020Article
- Varicella Zoster Virus Vasculitis and Adult Cerebrovascular Disease.The Neurohospitalist · 2019Review
- Vasopressor Therapy and the Brain: Dark Side of the Moon.Frontiers in medicine · 2019Review
- Cerebrovascular Manifestations of Lyme Neuroborreliosis-A Systematic Review of Published Cases.Frontiers in neurology · 2017Review
- Varicella Zoster Virus: A Common Cause of Stroke in Children and Adults.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2016Review
- High-resolution MRI vessel wall imaging in varicella zoster virus vasculopathy.Journal of the neurological sciences · 2015Article
- Unusual cause of cerebral vasospasm after pituitary surgery.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2011Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfections are a well-known cause of cerebral vasculopathy and vasculitis. We aimed to analyze the frequency of intracranial vasculopathy attributable to infection, the spectrum of causative microorganisms, imaging, and cerebrospinal fluid (CSF) characteristics as well as clinical course and outcome.
methodsWe used our institution's medical record system to identify all patients diagnosed with nonatherosclerotic central nervous system vasculopathy from January 1, 1999 through February 28, 2009. We reviewed their clinical charts, imaging data, and results of CSF studies.
resultsTwenty-five adult patients with nonatherosclerotic cerebral vasculopathy of large- and medium-sized intracranial vessels were identified. Eight patients had vasculopathy attributable to infection (32%). The underlying pathologies were acute bacterial meningitis (n = 4), varicella zoster virus (VZV) infection (n = 2), borreliosis (n = 1), and syphilis (n = 1). In six patients, magnetic resonance angiography was performed and showed vasculopathic changes in all patients examined (100%). In both patients with VZV-associated vasculopathy, the arterial wall enhanced on magnetic resonance imaging. The CSF examination of the patients with infectious vasculopathy showed a significantly higher white blood cell count. The outcome of the infectious cohort was unfavorable with one death, two patients with locked-in syndrome, and five patients discharged from intensive care with severe neurological deficits.
conclusionIn this cohort, one-third of all cases of nonatherosclerotic vasculopathy were due to infectious vasculopathy of large and medium intracranial vessels.
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