Evidence map›Paper›PMID 20146002›Full record

ArticleThe international journal of cardiovascular imaging2010

Low-dose CT and cardiac MR for the diagnosis of coronary artery disease: accuracy of single and combined approaches.

Hans Scheffel, Paul Stolzmann, Hatem Alkadhi, Naim Azemaj, André Plass, Stephan Baumueller, Lotus Desbiolles, Sebastian Leschka, Sebastian Kozerke, Volkmar Falk and 4 more

Open access · greenAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  5. Hybrid anatomo-functional imaging of coronary artery disease: Beneficial irrespective of its core components.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Review
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  13. Cardiovascular imaging 2010 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2011
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Hans ScheffelInstitute of Diagnostic Radiology, University Hospital Zurich, Raemistr 100, 8091, Zurich, Switzerland. hans.scheffel@usz.ch
Paul Stolzmann
Hatem Alkadhi
Naim Azemaj
André Plass
Stephan Baumueller
Lotus Desbiolles
Sebastian Leschka
Sebastian Kozerke
Volkmar Falk
Peter Boesiger
Christophe Wyss
Borut Marincek
Olivio F Donati
University Hospital of Zurich · CHETH Zurich · CHInstitute for Biomedical Engineering · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To prospectively compare the diagnostic performance of low-dose computed tomography coronary angiography (CTCA) and cardiac magnetic resonance imaging (CMR) and combinations thereof for the diagnosis of significant coronary stenoses. Forty-three consecutive patients with known or suspected coronary artery disease underwent catheter coronary angiography (CA), dual-source CTCA with prospective electrocardiography-gating, and cardiac CMR (1.5 Tesla). The following tests were analyzed: (1) low-dose CTCA, (2) adenosine stress-rest perfusion-CMR, (3) late gadolinium enhancement (LGE), (4) perfusion-CMR and LGE, (5) low-dose CTCA combined with perfusion-CMR, (5) low-dose CTCA combined with late gadolinium-enhancement, (6) low-dose CTCA combined with perfusion-CMR and LGE. CA served as the standard of reference. CA revealed >50% diameter stenoses in 68/129 (57.7%) coronary arteries in 29/43 (70%) patients. In the patient-based analysis, sensitivity, specificity, NPV and PPV of low-dose CTCA for the detection of significant stenoses were 100, 92.9, 100 and 96.7%, respectively. For perfusion-CMR and LGE, sensitivity, specificity, NPV, PPV, and accuracy were 89.7, 100, 82.4, and 100%, respectively. In the artery-based analysis, sensitivity and NPV of low-dose CTCA was significantly (P < 0.05) higher than that of perfusion-CMR and LGE. All combinations of low-dose CTCA and perfusion-CMR and/or LGE did not improve the diagnostic performance when compared to low-dose CTCA alone. Taking CA as standard of reference, low-dose CTCA outperforms CMR with regard to sensitivity and NPV, whereas CMR is more specific and has a higher PPV than low-dose CTCA.

Indexed as

AdenosineContrast MediaCoronary AngiographyCoronary DiseaseElectrocardiographyExercise TestFemaleHumansImage Interpretation, Computer-AssistedIohexolMagnetic Resonance AngiographyMaleMiddle AgedPredictive Value of TestsProspective StudiesRadiation DosageAdenosineContrast MediaIohexoliopromideVasodilator Agents

Identifiers

PMID20146002
OpenAlexW2039946962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.