ArticlePhysiotherapy Canada. Physiotherapie Canada2008
Eccentric exercise in patients with chronic health conditions: a systematic review.
Article in Physiotherapy Canada. Physiotherapie Canada, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04785469 (Impact of a Low-load Eccentric Training Program on Peripheral Muscle Function in Patients With Chronic Obstructive Pulmonary Disease), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of a Low-load Eccentric Training Program on Peripheral Muscle Function in Patients With Chronic Obstructive Pulmonary Disease
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- The Health and Functional Benefits of Eccentric versus Concentric Exercise Training: A Systematic Review and Meta-Analysis.Journal of sports science & medicine · 2023Pooled it
- Neuromuscular electrical stimulation for preventing skeletal-muscle weakness and wasting in critically ill patients: a systematic review.BMC medicine · 2013Pooled it
- Quercetin Modulates IGF-I and IGF-II Levels After Eccentric Exercise-Induced Muscle-Damage: A Placebo-Controlled Study.Frontiers in endocrinology · 2021Trial
- The effects of supramaximal versus submaximal intensity eccentric training when performed until volitional fatigue.European journal of applied physiology · 2017Trial
- The influence of resistance exercise with emphasis on specific contractions (concentric vs. eccentric) on muscle strength and post-exercise autonomic modulation: a randomized clinical trial.Brazilian journal of physical therapyTrial
- The effect of eccentric arm cycling on muscle damage and injury-related biomarkers.Clinical physiology and functional imaging · 2025Article
- Barriers to Exercise in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Patient Survey.Journal of clinical medicine research · 2024Article
- Time to consider the potential role of alternative resistance training methods in cancer management?Journal of sport and health science · 2023Review
- Skeletal effects of eccentric strengthening exercise: a scoping review.BMC musculoskeletal disorders · 2023Article
- The effect of therapeutic exercise in the prevention of lymphoedema secondary to breast cancer: a systematic review.Archives of medical science : AMS · 2023Review
- The chronic effects of eccentric exercise interventions in different populations: an umbrella review.European journal of translational myology · 2022Article
- Review
- Eccentric Exercise: Adaptations and Applications for Health and Performance.Journal of functional morphology and kinesiology · 2021Review
- The "Journal of functional morphology and kinesiology · 2020Article
- Aerobic Metabolic Adaptations in Endurance Eccentric Exercise and Training: From Whole Body to Mitochondria.Frontiers in physiology · 2020Review
- Eccentric Muscle Contractions: Risks and Benefits.Frontiers in physiology · 2019Review
- Downhill walking influence on physical condition and quality of life in patients with COPD: A randomized controlled trial.Medical journal of the Islamic Republic of Iran · 2018Article
- Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease.Frontiers in physiology · 2017Article
- Eccentric Exercise Program Design: A Periodization Model for Rehabilitation Applications.Frontiers in physiology · 2017Article
- Does Downhill Walking on Treadmill Improve Physical Status and Quality of Life of A Patient With COPD?Asian journal of sports medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe capacity of eccentric actions to produce muscle hypertrophy, strength gains, and neural adaptations without stressing the cardiopulmonary system has led to the prescription of eccentric training programmes in patients with low tolerance to exercise, such as elders or those with chronic health conditions. The purpose of this systematic review was to analyze the evidence regarding the effectiveness and suitability of eccentric training to restore musculoskeletal function in patients with chronic diseases. SUMMARY OF KEY POINTS: Relevant articles were identified from nine databases and from the reference lists of key articles. Articles were assessed to determine level of evidence and scientific rigour. Nine studies met the inclusion criteria. According to Sackett's levels of evidence, 7 studies were graded at level IIb, 1 study at level IV, and the remaining study at level V. Articles were also graded for scientific rigour according to the PEDro scale. One study was rated as high quality, 4 studies were rated as moderate, and 2 studies were graded as poor quality.
conclusionsEccentric training may be safely used to restore musculoskeletal function in patients with some specific chronic conditions. However, the heterogeneity of diseases makes it very difficult to extrapolate results and to standardize clinical recommendations for adequate implementation of this type of exercise. More studies are needed to establish the potential advantages of eccentric training in chronic conditions.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.