ArticleJournal of diabetes science and technology2009
Measurement of glycated hemoglobin A1c from dried blood by turbidimetric immunoassay.
Article in Journal of diabetes science and technology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Dried Blood Spots to Assess Cardiovascular-Kidney-Metabolic Health.Journal of the American Heart Association · 2025Pooled it
- Addressing asthma and obesity in children with community health workers: proof-of-concept intervention development.BMC pediatrics · 2016Trial
- Abnormally Low HbABritish journal of biomedical science · 2024Review
- Advances in electrochemical biosensors employing carbon-based electrodes for detection of biomarkers in diabetes mellitus.ADMET & DMPK · 2024Review
- Detection of Biomarker Using Aptasensors to Determine the Type of Diabetes.Diagnostics (Basel, Switzerland) · 2023Review
- Dairy product consumption and incident prediabetes in Dutch middle-aged adults: the Hoorn Studies prospective cohort.European journal of nutrition · 2022Article
- HbADiabetic medicine : a journal of the British Diabetic Association · 2020Article
- Adherence to a food group-based dietary guideline and incidence of prediabetes and type 2 diabetes.European journal of nutrition · 2020Article
- Dried Blood Spot in Laboratory: Directions and Prospects.Diagnostics (Basel, Switzerland) · 2020Review
- Serum omentin-1 levels in type 2 diabetic obese women in relation to glycemic control, insulin resistance and metabolic parameters.Journal of clinical & translational endocrinology · 2018Article
- Optimization of extraction of genomic DNA from archived dried blood spot (DBS): potential application in epidemiological research & bio banking.Gates open research · 2018Article
- Depressive Symptoms During Adolescence and Young Adulthood and the Development of Type 2 Diabetes Mellitus.American journal of epidemiology · 2016Article
- Innovations in health and demographic surveillance systems to establish the causal impacts of HIV policies.Current opinion in HIV and AIDS · 2015Review
- Inability of Turbidimetry Method in Detecting Glycated Hemoglobin to Select Diabetes Mellitus Patients According to Their Concentrations of Blood Glucose Levels.Journal of clinical laboratory analysis · 2015Article
- Measurement of HbA1c in Gingival Crevicular Blood Using a High-Pressure Liquid Chromatography Procedure.Laboratory medicine · 2015Article
- The use of dried blood spot sampling for the measurement of HbA1c: a cross-sectional study.BMC clinical pathology · 2015Article
- Article
- Comparability of HbA1c and lipids measured with dried blood spot versus venous samples: a systematic review and meta-analysis.BMC clinical pathology · 2014Article
- Analysis of hemoglobin A1c from dried blood spot samples with the Tina-quantR II immunoturbidimetric method.Journal of diabetes science and technology · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlycated hemoglobin A1c (A1C) is an important marker in the diagnosis and treatment of diabetes. Dried blood measurement of A1C is useful in large scale epidemiological evaluation of A1C, especially to assess the impact of intervention programs. The possibility of using dried blood for measurement of A1C by the immunoturbidimetric method was explored in the present study.
methodBlood was collected from 30 patients, and blood spots were prepared and dried. The dried blood spot samples were kept for different lengths of time at 4 degrees C to assess stability. Glycated hemoglobin was measured in whole blood and dried blood on the day of collection as well as on days 10 and 15 by immunoturbidimetric method.
resultsThe A1C values of 30 samples analyzed for comparison between whole blood estimation and dried blood ranged from 4.6% to 9.9%. The mean A1C on the day of sample collection was 6.01% +/- 1.58% in fresh whole blood samples and 5.94% +/- 1.58 % in dried blood spots. A linear and highly correlated relationship was observed between dried blood A1C values and those in whole blood (r = 0.986 and intraclass correlation value = 0.993). Glycated hemoglobin values on day 10 and day 15 were comparable with the values on day 1 with a shift in mean of just 1% on day 10 and 3.04% on day 15.
conclusionIn conclusion, dried blood can be used for measurement of A1C by immunoturbidimetric method, and further stability of A1C measurement from dried blood for up to 15 days at 4 degrees C makes it an ideal matrix for transportation in developing countries like India.
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