ReviewPharmaceutical research2010
Electrospun nanofibers in oral drug delivery.
Review in Pharmaceutical research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- New dimensions of electrospun nanofiber material designs for biotechnological uses.Trends in biotechnology · 2024Review
- Advances and Prospects of Prolamine Corn Protein Zein as Promising Multifunctional Drug Delivery System for Cancer Treatment.International journal of nanomedicine · 2023Review
- Utilising Co-Axial Electrospinning as a Taste-Masking Technology for Paediatric Drug Delivery.Pharmaceutics · 2021Article
- Scale-up of Electrospinning: Market Overview of Products and Devices for Pharmaceutical and Biomedical Purposes.Pharmaceutics · 2021Review
- Alginate Nanoformulation: Influence of Process and Selected Variables.Pharmaceuticals (Basel, Switzerland) · 2020Review
- Micro and nanoscale technologies in oral drug delivery.Advanced drug delivery reviews · 2020Review
- Fabrication and Characterization of Electrospun Nanofibers for the Modified Release of the Chronobiotic Hormone Melatonin.Current drug delivery · 2019Article
- Mucoadhesive electrospun nanofibers for drug delivery systems: applications of polymers and the parameters' roles.International journal of nanomedicine · 2019Review
- Doxycycline release and antibacterial activity from PMMA/PEO electrospun fiber mats.Journal of applied oral science : revista FOB · 2019Article
- Homogenization of Amorphous Solid Dispersions Prepared by Electrospinning in Low-Dose Tablet Formulation.Pharmaceutics · 2018Article
- Antimicrobial and Wound Healing Properties of Polyacrylonitrile-Moringa Extract Nanofibers.ACS omega · 2018Article
- Preparation of glutinous rice starch/polyvinyl alcohol copolymer electrospun fibers for using as a drug delivery carrier.Asian journal of pharmaceutical sciences · 2018Article
- pH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms.Drug delivery · 2017Review
- High-throughput and high-yield fabrication of uniaxially-aligned chitosan-based nanofibers by centrifugal electrospinning.Carbohydrate polymers · 2015Article
- Mussel-inspired protein-mediated surface functionalization of electrospun nanofibers for pH-responsive drug delivery.Acta biomaterialia · 2014Article
- Electrospun formulations containing crystalline active pharmaceutical ingredients.Pharmaceutical research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to enhance the delivery of drugs with limited absorption due to poor solubility/dissolution, approaches are being developed to improve the dissolution rates and solubility of drug molecules. These approaches include identification of water-soluble salts of parent drugs, preparation of stable amorphous drug formulations, inclusion of solubility-enhancing agents in the dosage form, and particle size reduction. Technologies to reduce drug particle size to sub-micrometer range are being applied to product development more frequently. Electrospinning is being considered as one of the technologies which can produce nanosized drugs incorporated in polymeric nanofibers. In vitro and in vivo studies have demonstrated that the release rates of drugs from these nanofiber formulations are enhanced compared to those from original drug substance. This technology has the potential to be used for enhancing the oral delivery of poorly soluble drugs.
Indexed as
Identifiers
20143253What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.