ArticleInflammopharmacology2010
Relevance of Helicobacter pylori genotypes in gastric pathology and its association with plasma malondialdehyde and nitric oxide levels.
Article in Inflammopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- The association betweenJournal of medicine and life · 2026Article
- Emerging contaminants in healthcare effluents: antibiotic resistance and virulence factor dissemination.Folia microbiologica · 2025Review
- Increased Oxidative Stress in Gastric Cancer Patients and Their First-Degree Relatives: A Prospective Study from Northeastern Brazil.Oxidative medicine and cellular longevity · 2021Article
- Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan againstJournal of veterinary science · 2020Article
- IGF-1 overexpression improves mesenchymal stem cell survival and promotes neurological recovery after spinal cord injury.Stem cell research & therapy · 2019Article
- Functional variants of lncRNA LINC00673 and gastric cancer susceptibility: a case-control study in a Chinese population.Cancer management and research · 2019Article
- Observational
- Effect of H. pylori Infection on Cytokine Profiles and Oxidative Balance in Subjects with Chronic Alcohol Ingestion.PloS one · 2015Article
- Helicobacter pylori and gastric cancer: Indian enigma.World journal of gastroenterology · 2014Review
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Persistent infection with Helicobacter pylori confers an increased risk of peptic ulceration and gastric adenocarcinoma. Reactive oxygen and nitrogen species play a crucial role in the progression from normal gastric mucosa to cancer. The aim of the present study was to investigate the plasma malondialdehyde and nitric oxide levels in H. pylori related gastroduodenal diseases and associate their levels with gastric pathology and genotypes of H. pylori. Malondialdehyde and nitric oxide levels in plasma samples of 250 subjects were spectrophotometrically determined. Subsequently, genotypic and histopathological assessment was performed in gastric biopsies obtained during endoscopy. The levels of MDA and NO exceeded in subjects infected with genotype-1 of Hp than those with other genotypes suggesting more precise interaction of highly virulent strains of Hp in eliciting severe tissue damage. In conclusion, the study demonstrates close relationship between the plasma malondialdehyde and nitric oxide levels, gastric histopathology and genotypes of H. pylori.
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