ArticleInternational journal of legal medicine2010
Potentials and limits of pairwise kinship analysis using autosomal short tandem repeat loci.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bibliometric analysis of kinship analysis from 1960 to 2023: global trends and development.Frontiers in genetics · 2024Pooled it
- Beyond the Core: The Role of Supplementary Short Tandem Repeats in Forensic Genetics.International journal of molecular sciences · 2026Review
- Population substructure affects kinship testing in multi-ethnic areas of China.International journal of legal medicine · 2026Article
- Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications.Human genomics · 2025Article
- Implementation of NGS and SNP microarrays in routine forensic practice: opportunities and barriers.BMC genomics · 2025Review
- Considerations for the Implementation of Massively Parallel Sequencing into Routine Kinship Analysis.Genes · 2025Article
- Review
- Population-scale whole genome sequencing identifies 271 highly polymorphic short tandem repeats from Japanese population.Heliyon · 2018Article
- The likelihood ratio as a random variable for linked markers in kinship analysis.International journal of legal medicine · 2016Article
- A SNP panel for identity and kinship testing using massive parallel sequencing.International journal of legal medicine · 2016Article
- Kinship analysis: assessment of related vs unrelated based on defined pedigrees.International journal of legal medicine · 2016Article
- Exclusion probabilities and likelihood ratios with applications to mixtures.International journal of legal medicine · 2016Article
- Analysis of linkage and linkage disequilibrium for syntenic STRs on 12 chromosomes.International journal of legal medicine · 2014Article
- Exclusion probabilities and likelihood ratios with applications to kinship problems.International journal of legal medicine · 2014Article
- Assessment of application value of 19 autosomal short tandem repeat loci of GoldenEye 20A kit in forensic paternity testing.International journal of legal medicine · 2013Article
- Comparative evaluation of alternative batteries of genetic markers to complement autosomal STRs in kinship investigations: autosomal indels vs. X-chromosome STRs.International journal of legal medicine · 2012Article
- Combining results of forensic STR kits: HDplex validation including allelic association and linkage testing with NGM and Identifiler loci.International journal of legal medicine · 2012Article
- Kinship Analysis with Diallelic SNPs - Experiences with the SNPforID Multiplex in an ISO17025 Accreditated Laboratory.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2012Article
- SNPs as Supplements in Simple Kinship Analysis or as Core Markers in Distant Pairwise Relationship Tests: When Do SNPs Add Value or Replace Well-Established and Powerful STR Tests?Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2012Article
- Mutation analysis of 24 short tandem repeats in Chinese Han population.International journal of legal medicine · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At least in principle, most instances of complex kinship testing can be reduced to pairwise kinship cases involving two critical family members that either link or separate presumed sub-branches of a family. In the European population, the 34 short tandem repeats (STRs) currently used in forensic genetics are sufficiently powerful to allow assessment of disputed first and second but not lower degrees of pairwise blood relatedness. We provide estimates of the means and variances of marker-specific log-likelihood ratios, using large-sample approximation and assuming different scenarios of pairwise kinship analysis. These estimates allow power calculations to be performed for any combination of the available STRs. Since some of the markers considered are physically linked, chromosome-wide likelihood calculations in kinship cases other than parent-child duos (and trios) have to take the reduced rates of meiotic inter-marker recombination into account. We show by simulation that this requirement may be ignored when discriminating distant hypotheses about kinship, but that linkage may play an important role in the biostatistical analysis of more intricate cases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.