ArticleInternational journal of diabetes in developing countries2009
Lipoprotein (a) in type 2 diabetes mellitus: Relation to LDL:HDL ratio and glycemic control.
Article in International journal of diabetes in developing countries, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Elevated serum lipoprotein(a) levels as a potential risk factor for diabetic retinopathy in type 2 diabetes: a meta-analysis.International ophthalmology · 2024Pooled it
- Effects of mobile health interventions on health-related outcomes in older adults with type 2 diabetes: A systematic review and meta-analysis.Journal of diabetes · 2023Pooled it
- Nonsevere Burn Induces a Prolonged Systemic Metabolic Phenotype Indicative of a Persistent Inflammatory Response Postinjury.Journal of proteome research · 2024Article
- Lipoprotein(a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options.Annals of medicine · 2020 · on this mapReview
- Are diabetes mellitus and lipoprotein(a) independently or causally associated with an increased cardiovascular risk?Anatolian journal of cardiology · 2017Article
- Lipoprotein (a): impact by ethnicity and environmental and medical conditions.Journal of lipid research · 2016Review
- Serum Lipoprotein (a) Levels in Black South African Type 2 Diabetes Mellitus Patients.Oxidative medicine and cellular longevity · 2016Article
- Lipoprotein (a) and atherogenic indices in Sudanese patients with type 2 diabetes.International journal of health sciences · 2014Article
- Lipoprotein(a) is not related to markers of insulin resistance in pregnancy.Cardiovascular diabetology · 2013Article
- Plasma lipoprotein(a) levels in patients with slow coronary flow.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2013Article
- Lipoprotein(a) in type 2 diabetic subjects and its relationship to diabetic microvascular complications.World journal of diabetes · 2012Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreased lipoprotein (a) [Lp (a)] concentrations are predictive of coronary artery disease (CAD). Type 2 diabetes mellitus also leads to dyslipidemia, like elevated triglyceride levels and low HDL levels, which are known risk factors for CAD. This study was designed to investigate the levels of Lp (a) in type 2 diabetic patients and their association with LDL: HDL ratio and glycemic control. MATERIALS AND
methodsThe study included 60 patients of type 2 diabetes and 50 age and sex matched controls. The Lp(a) levels in the diabetic group were compared with the control group and the relationship between the Lp(a) levels and LDL: HDL ratio was evaluated. Diabetic group was further divided into three subgroups according to levels of glycated hemoglobin. Lp(a) levels and glycated hemoglobin in controlled and uncontrolled diabetes mellitus were also compared to find out any correlation between them. Statistical analysis was done using the students 't' test and Chi square test.
resultsLp(a) levels were found to be significantly increased in the diabetic group as compared to the control group (P< 0.001). LDL: HDL ratio was also increased in the diabetic group as compared to the control group. Lp(a) levels showed no association with LDL: HDL ratio and degree of glycemic control in these patients.
conclusionsThe results of the present study suggest that Lp(a) levels are increased in type 2 diabetic patients. The elevated Lp(a) levels do not reflect the glycemic status and are also independent of increase in LDL:HDL ratio suggesting different metabolic pathways and the genetic connection for LDL and Lp(a).
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