ArticleProceedings of the National Academy of Sciences of the United States of America2010
A developmental framework for endodermal differentiation and polarity.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
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94 citing papers in PubMed, 215 citations in OpenAlex.
- Quantification of cell-type-specific plasmodesmata distribution in Arabidopsis roots reveals spatial and patterning dynamics.The Plant journal : for cell and molecular biology · 2026Article
- Unraveling the role of OsPIP1;3 in arsenic transport in rice (Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Canonical tyrosine-based motifs are required for constitutive endocytosis and polarity of IRT1 and contribute to metal uptake.The Plant journal : for cell and molecular biology · 2025Article
- Regulation and function of a polarly localized lignin barrier in the exodermis.Nature plants · 2025Article
- Arabidopsis KNS3 and its two homologs mediate endoplasmic reticulum-to-plasma membrane traffic of boric acid channels.Journal of experimental botany · 2024Article
- The transcriptional integration of environmental cues with root cell type development.Plant physiology · 2024Review
- Comparisons of two receptor-MAPK pathways in a single cell-type reveal mechanisms of signalling specificity.Nature plants · 2024Article
- Guidelines for naming and studying plasma membrane domains in plants.Nature plants · 2024Review
- Recent progress in understanding the cellular and genetic basis of plant responses to low oxygen holds promise for developing flood-resilient crops.Journal of experimental botany · 2024Article
- Plasma membrane intrinsic protein OsPIP2;6 is involved in root-to-shoot arsenic translocation in rice (Oryza sativa L.).Plant cell reports · 2024Article
- Polar localization of a rice silicon transporter requires isoleucine at both C- and N-termini as well as positively charged residues.The Plant cell · 2023Article
- Directed growth and fusion of membrane-wall microdomains requires CASP-mediated inhibition and displacement of secretory foci.Nature communications · 2023Article
- MCU proteins dominate in vivo mitochondrial Ca2+ uptake in Arabidopsis roots.The Plant cell · 2022Article
- Transcriptional networks regulating suberin and lignin in endodermis link development and ABA response.Plant physiology · 2022Article
- Development and diversity of lignin patterns.Plant physiology · 2022Article
- Comprehensive Expression Analyses of Plastidial Thioredoxins ofAntioxidants (Basel, Switzerland) · 2022Article
- A dirigent family protein confers variation of Casparian strip thickness and salt tolerance in maize.Nature communications · 2022Article
- Suberin Biosynthesis, Assembly, and Regulation.Plants (Basel, Switzerland) · 2022Review
- Microtubule-based perception of mechanical conflicts controls plant organ morphogenesis.Science advances · 2022Article
- Imaging the living plant cell: From probes to quantification.The Plant cell · 2022Review
34 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endodermis is a root cell layer common to higher plants and of fundamental importance for root function and nutrient uptake. The endodermis separates outer (peripheral) from inner (central) cell layers by virtue of its Casparian strips, precisely aligned bands of specialized wall material. Here we reveal that the membrane at the Casparian strip is a diffusional barrier between the central and peripheral regions of the plasma membrane and that it mediates attachment to the extracellular matrix. This membrane region thus functions like a tight junction in animal epithelia, although plants lack the molecular modules that establish tight junction in animals. We have also identified a pair of influx and efflux transporters that mark both central and peripheral domains of the plasma membrane. These transporters show opposite polar distributions already in meristems, but their localization becomes refined and restricted upon differentiation. This "central-peripheral" polarity coexists with the apical-basal polarity defined by PIN proteins within the same cells, but utilizes different polarity determinants. Central-peripheral polarity can be already observed in early embryogenesis, where it reveals a cellular polarity within the quiescent center precursor cell. A strict diffusion block between polar domains is common in animals, but had never been described in plants. Yet, its relevance to endodermal function is evident, as central and peripheral membranes of the endodermis face fundamentally different root compartments. Further analysis of endodermal transporter polarity and manipulation of its barrier function will greatly promote our understanding of plant nutrition and stress tolerance in roots.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.