Evidence map›Paper›PMID 20142020›Full record

ArticleJournal of cardiac failure2010

Left ventricular remodeling and myocardial recovery on mechanical circulatory support.

Marc A Simon, Brian A Primack, Jeffrey Teuteberg, Robert L Kormos, Christian Bermudez, Yoshiya Toyoda, Hemal Shah, John Gorcsan, Dennis M McNamara

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of cardiac failure, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Emergent decommissioning of HeartMate 3 for life-threatening hemorrhage.Journal of vascular surgery cases and innovative techniques · 2024
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Preoperative beta-blocker treatment is a key for deciding left ventricular assist device implantation strategy as a bridge to recovery.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Marc A SimonCardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA. simonma@upmc.edu
Brian A Primack
Jeffrey Teuteberg
Robert L Kormos
Christian Bermudez
Yoshiya Toyoda
Hemal Shah
John Gorcsan
Dennis M McNamara
University of Pittsburgh · US

Funding

University of Pittsburgh Clinical and Translational Science InstitutionKL2RR024154 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$22.2M
University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
Identifying and Facilitating Ventricular Recovery on Mechanical SupportR01HL086918 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GORCSAN, JOHN · 2007 to 2011
$3.8M
Genetic Modulation of Left Ventricular RecoveryR01HL075038 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MCNAMARA, DENNIS M. · 2004 to 2008
$1.8M
Racial Genomic Differences and Heart Failure OutcomesK24HL069912 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MCNAMARA, DENNIS M. · 2002 to 2013
$1.4M
CARDIAC PERFORMANCE BY QUANTITATIVE ECHOCARDIOGRAPHYK24HL004503 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GORCSAN, JOHN · 2001 to 2010
$1.3M
Media Literacy to Prevent Adolescent Smoking InitiationK07CA114315 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PRIMACK, BRIAN A. · 2006 to 2010
$766k
NCATS NIH HHS KL2 TR000146NCI NIH HHS K07 CA114315NCI NIH HHS K07-CA114315NCRR NIH HHS KL2 RR024154NHLBI NIH HHS K24 HL004503NHLBI NIH HHS K24 HL04503NHLBI NIH HHS K24 HL069912NHLBI NIH HHS K24 HL069912.NHLBI NIH HHS L30 HL078435NHLBI NIH HHS R01 HL075038NHLBI NIH HHS R01 HL086918NHLBI NIH HHS R01 HL75038
6 · The paper itself

Abstract

backgroundMyocardial recovery after ventricular assist devices (VAD) is rare but appears more common in nonischemic cardiomyopathies (NICM). We sought to evaluate left ventricular (LV) end diastolic diameter (LVEDD) for predicting recovery after VAD. METHODS AND

resultsNICM patients receiving long-term mechanical support between 1996 and 2008 were reviewed. Subjects were divided into 3 groups: mild, moderate, and severe dilation (Group A: LVEDD <6.0 cm [n = 22]; Group B: 6.0-7.0 cm [n = 32]; Group C: >7.0 cm [n = 48], respectively). Overall, recovery (successful explant without transplantation) occurred in 14 of 102 subjects (14%). Of these, 2 died and 2 required transplantation within 1 year. Recovery was more common in patients without LV dilation (Groups A/B/C = 32%/22%/0%, P < .001), as was sustained recovery (alive and transplant free 1 year after explant; A/B/C = 27%/10%/0%, P = .001). Of the recovery patients in Group A, 6/7 (86%) had sustained recovery versus 3/6 (50%) in Group B.

conclusionsRecovery occurred in 32% of NICM patients without significant LV dilation at time of VAD, the majority of whom experienced significant sustained recovery. Recovery was not evident in those with severe LV dilation. Routine echocardiography at the time of implant may assist in targeting patients for recovery after VAD.

Indexed as

Heart-Assist DevicesMyocardiumAdultCardiomyopathiesCohort StudiesFemaleHumansMaleMiddle AgedProspective StudiesRecovery of FunctionVentricular Dysfunction, LeftVentricular Remodeling

Identifiers

PMID20142020
PMCPMC2819986
OpenAlexW2099522121

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.