Evidence map›Paper›PMID 20141097›Full record

ReviewAmerican family physician2009

Cardiomyopathy: an overview.

Randell K Wexler, Terry Elton, Adam Pleister, David Feldman

Open access · greenAbstract readReview
In one paragraph

Review in American family physician, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 4 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Native TJournal of magnetic resonance imaging : JMRI · 2018
    Pooled it
  4. Pacing for drug-refractory or drug-intolerant hypertrophic cardiomyopathy.The Cochrane database of systematic reviews · 2012
    Pooled it
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Missense variants in the myosin binding domains ofbioRxiv : the preprint server for biology · 2025
    Article
  14. Review
  15. Review
  16. Cardiomyopathies and a brief insight into DOX-induced cardiomyopathy.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  17. Article
  18. Article
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Randell K WexlerThe Ohio State University, 456 W. 10th Ave., Columbus, OH 43210, USA. randy.wexler@osumc.edu
Terry Elton
Adam Pleister
David Feldman
The Ohio State University · US

Funding

HUMAN ANGIOTENSIN II RECEPTOR GENE REGULATIONR01HL048848 · NHLBI · OHIO STATE UNIVERSITY · PI ELTON, TERRY S · 1997 to 2009
$2.1M
NHLBI NIH HHS R01 HL048848
6 · The paper itself

Abstract

Cardiomyopathy is an anatomic and pathologic diagnosis associated with muscle or electrical dysfunction of the heart. Cardiomyopathies represent a heterogeneous group of diseases that often lead to progressive heart failure with significant morbidity and mortality. Cardiomyopathies may be primary (i.e., genetic, mixed, or acquired) or secondary (e.g., infiltrative, toxic, inflammatory). Major types include dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy. Although cardiomyopathy is asymptomatic in the early stages, symptoms are the same as those characteristically seen in any type of heart failure and may include shortness of breath, fatigue, cough, orthopnea, paroxysmal nocturnal dyspnea, and edema. Diagnostic studies include B-type natriuretic peptide levels, baseline serum chemistries, electrocardiography, and echocardiography. Treatment is targeted at relieving the symptoms of heart failure and reducing rates of heart failure-related hospitalization and mortality. Treatment options include pharmacotherapy, implantable cardioverter-defibrillators, cardiac resynchronization therapy, and heart transplantation. Recommended lifestyle changes include restricting alcohol consumption, losing weight, exercising, quitting smoking, and eating a low-sodium diet.

Indexed as

AlgorithmsAntihypertensive AgentsCardiomyopathiesHeart FailureHumansNatriuretic Peptide, BrainRisk Reduction BehaviorAntihypertensive AgentsNatriuretic Peptide, Brain

Identifiers

PMID20141097
PMCPMC2999879
OpenAlexW108613969

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.