ArticlePediatric surgery international2010
LigaSure compared with ligatures and endoclips in experimental appendectomy: how safe is it?
Article in Pediatric surgery international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Efficacy of the LigaSure system vs UltraCision harmonic scalpel in laparoscopic appendectomy for the management of acute appendicitis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2026Article
- Evaluation of the Appropriate LigaSure™ Device to Transect the Appendix-A Comparison between 5 mm and 10 mm Laparoscopic Devices in an Ex Vivo Trial.Medicina (Kaunas, Lithuania) · 2023Article
- Evaluation of the LigaSure(™) Vessel Sealing System for bowel transection and intestinal anastomosis-an experimental study in a porcine model.Langenbeck's archives of surgery · 2016Article
- Surgical Efficacy Among Laparoscopic Ultrasonic Dissectors: Are We Advancing Safely? A Review of Literature.Journal of obstetrics and gynaecology of India · 2015Review
- Methods for closure of appendix stump during laparoscopic appendectomy procedure.Ulusal cerrahi dergisi · 2015Review
- Single incision cholecystectomy using a clipless technique with LigaSure in a resource limited environment: The Bahamas experience.International journal of surgery case reports · 2015Article
- Development of a standardized laparoscopic caecum resection model to simulate laparoscopic appendectomy in rats.European journal of medical research · 2014Article
- Colorectal anastomosis facilitated by the use of the LigaSure(®) sealing device: comparative study in an animal model.Surgical endoscopy · 2014Article
- Use of the LigaSure device and the Stapler for closure of the small bowel: a comparative ex vivo study.Surgery today · 2013Article
- Comparison of lateral thermal damage of the human peritoneum using monopolar diathermy, Harmonic scalpel and LigaSure.Canadian journal of surgery. Journal canadien de chirurgie · 2012Article
- The impact of surgeon choice on the cost of performing laparoscopic appendectomy.Surgical endoscopy · 2011Article
- Closure of the cystic duct during laparoscopic cholecystectomy in children using the LigaSure Vessel Sealing System.World journal of surgery · 2011Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study aims to compare strength, healing, and inflammation of appendiceal stumps closed by LigaSure Precise (Valleylab, Boulder, CO, USA) device, ligatures using polyglactin 910 (Vicryl, Ethicon, Edinburgh, UK) and endoclips (Ligaclip ERCA, Ethicon, OH, USA), and operation time (OT) in experimental appendectomy.
methodsForty-eight Sprague-Dawley rats were divided into two (Group A and B). Each group was further subdivided into three subgroups (AS, AC, AL, BS, BC, BL) containing eight rats. Appendectomy was performed and stump was closed by ligatures in S, by endoclips in C and by LigaSure in L subgroups. OT was recorded. In Group A, cecum bursting pressures (BP) were determined instantly after the operation. In Group B, BP, histological evaluations, and measurements of collagen contents estimated by the tissue hydroxyproline (HPL) level were made on the seventh postoperative day. Statistical analyses were performed with Kruskal-Wallis test and Mann-Whitney U test. P value was considered significant at less than 0.05.
resultsBPs of subgroups were comparable on postoperative immediate period and day 7. HPLs and OTs were significantly better in L subgroups. BL had the least inflammation.
conclusionBetter healing, less inflammation, shorter OT, and equal strength achieved with LigaSure device comparing with polyglactin 910 ties and endoclips in experimental appendectomy is encouraging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.