Evidence map›Paper›PMID 20140722›Full record

ArticleFolia microbiologica2009

Probiotic Lactobacillus strains: in vitro and in vivo studies.

B Cukrowska, I Motyl, H Kozáková, M Schwarzer, R K Górecki, E Klewicka, K Slizewska, Z Libudzisz

Abstract read
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Article in Folia microbiologica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Bacteriocin-Producing StrainFoods (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Anti-Salmonella Potential of NewPolish journal of microbiology · 2020
    Article
  7. Frontiers in microbiology · 2017
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B CukrowskaDepartment of Pathology, The Children's Memorial Health Institute, Warsaw, Poland. b.cukrowska@czd.pl
I Motyl
H Kozáková
M Schwarzer
R K Górecki
E Klewicka
K Slizewska
Z Libudzisz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three Lactobacillus strains (LOCK 0900, LOCK 0908, LOCK 0919) out of twenty-four isolates were selected according to their antagonistic activity against pathogenic bacteria, resistance to low pH and milieu of bile salts. Intragastric administration of a mixture of these strains to Balb/c mice affected cytokine T(H)1-T(H)2 balance toward nonallergic T(H)1 response. Spleen cells, isolated from lactobacilli-treated mice and re-stimulated in vitro with the mixture of heat-inactivated tested strains, produced significantly higher amounts of anti-allergic tumor necrosis factor- and interferon-gamma than control animals whereas the level of pro-allergic interleukin-5 was significantly lower. Lactobacillus cells did not translocate through the intestinal barrier into blood, liver and spleen; a few Lactobacillus cells found in mesenteric lymph nodes could create antigenic reservoir activating the immune system. The mixture of Lactobacillus LOCK 0900, LOCK 0908 and LOCK 0919 strains represents a probiotic bacterial preparation with possible use in prophylaxis and/or therapy of allergic diseases.

Indexed as

AcidsAnimalsAnti-Bacterial AgentsAntibiosisBacterial TranslocationBile Acids and SaltsBloodCells, CulturedInterferon-gammaInterleukin-5LactobacillusLeukocytes, MononuclearLiverMiceMice, Inbred BALB CProbioticsAcidsAnti-Bacterial AgentsBile Acids and SaltsInterferon-gammaInterleukin-5Tumor Necrosis Factor-alpha

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.