ReviewPflugers Archiv : European journal of physiology2010
Gap junctions in inherited human disease.
Review in Pflugers Archiv : European journal of physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Gap junctions in Turing-type periodic feather pattern formation.PLoS biology · 2024Article
- Endothelial Connexins in Developmental and Pathological Angiogenesis.Cold Spring Harbor perspectives in medicine · 2022Review
- Ouabain Enhances Gap Junctional Intercellular Communication by Inducing Paracrine Secretion of Prostaglandin E2.International journal of molecular sciences · 2021Article
- Involvement of gap junctions in propylthiouracil-induced cytotoxicity in BRL-3A cells.Experimental and therapeutic medicine · 2019Article
- A Cell-Based Assay to Assess Hemichannel Function.The Yale journal of biology and medicine · 2017Review
- Article
- Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness.Pflugers Archiv : European journal of physiology · 2016Article
- Gold nanoparticle-mediated (GNOME) laser perforation: a new method for a high-throughput analysis of gap junction intercellular coupling.Journal of bioenergetics and biomembranes · 2015Article
- Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo.Molecular biology of the cell · 2014Article
- Involvement of gap junction channels in the pathophysiology of migraine with aura.Frontiers in physiology · 2014Review
- Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing.Frontiers in physiology · 2014Review
- Functional analysis and regulation of purified connexin hemichannels.Frontiers in physiology · 2014Review
- Gap junctional communication in health and disease.Frontiers in physiology · 2014Article
- Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos.Frontiers in physiology · 2014Article
- The Concise Guide to PHARMACOLOGY 2013/14: ion channels.British journal of pharmacology · 2013Article
- Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46.American journal of physiology. Cell physiology · 2013Article
- Connexin 43 a check-point component of cell proliferation implicated in a wide range of human testis diseases.Cellular and molecular life sciences : CMLS · 2013Review
- An Escherichia coli strain for expression of the connexin45 carboxyl terminus attached to the 4th transmembrane domain.Frontiers in pharmacology · 2013Article
- Cell-to-cell communication in plants, animals, and fungi: a comparative review.Die Naturwissenschaften · 2013Review
- Gap junctions in inherited human disorders of the central nervous system.Biochimica et biophysica acta · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gap junctions (GJ) provide direct intercellular communication. The structures underlying these cell junctions are membrane-associated channels composed of six integral membrane connexin (Cx) proteins, which can form communicating channels connecting the cytoplasms of adjacent cells. This provides coupled cells with a direct pathway for sharing ions, nutrients, or small metabolites to establish electrical coupling or balancing metabolites in various tissues. Genetic approaches have uncovered a still growing number of mutations in Cxs related to human diseases including deafness, skin disease, peripheral and central neuropathies, cataracts, or cardiovascular dysfunctions. The discovery of a growing number of inherited human disorders provides an unequivocal demonstration that gap junctional communication is crucial for diverse physiological processes.
Indexed as
Identifiers
20140684What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.