ArticleInternational journal of legal medicine2010
The mtDNA composition of Uzbekistan: a microcosm of Central Asian patterns.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Genetic Continuity of Bronze Age Ancestry with Increased Steppe-Related Ancestry in Late Iron Age Uzbekistan.Molecular biology and evolution · 2021Article
- Article
- Current pool of ultimate collection of mitochondrial DNA from remnants of Kalash.Mitochondrial DNA. Part B, Resources · 2021Article
- Mitochondrial DNA diversity in the Khattak and Kheshgi of the Peshawar Valley, Pakistan.Genetica · 2020Article
- Neolithic phylogenetic continuity inferred from complete mitochondrial DNA sequences in a tribal population of Southern India.Genetica · 2018Article
- Maternal genetic features of the Iron Age Tagar population from Southern Siberia (1st millennium BC).PloS one · 2018Article
- The Connection of the Genetic, Cultural and Geographic Landscapes of Transoxiana.Scientific reports · 2017Article
- Phylogeography, genetic diversity and demographic history of the Iranian Kurdish groups based on mtDNA sequences.Journal of genetics · 2016Article
- Ancient mitochondrial genome reveals trace of prehistoric migration in the east Pamir by pastoralists.Journal of human genetics · 2016Article
- The Potential Contribution of BRCA Mutations to Early Onset and Familial Breast Cancer in Uzbekistan.Central Asian journal of global health · 2016Article
- Echoes from Sepharad: signatures on the maternal gene pool of crypto-Jewish descendants.European journal of human genetics : EJHG · 2015Article
- Mitochondrial DNA variation, genetic structure and demographic history of Iranian populations.Molecular biology research communications · 2014Article
- Large-scale mitochondrial DNA analysis in Southeast Asia reveals evolutionary effects of cultural isolation in the multi-ethnic population of Myanmar.BMC evolutionary biology · 2014Article
- Article
- Article
- Complete mitochondrial DNA diversity in Iranians.PloS one · 2013Article
- Complete mitochondrial DNA analysis of eastern Eurasian haplogroups rarely found in populations of northern Asia and eastern Europe.PloS one · 2012Article
- Forensic and genetic characterization of mtDNA from Pathans of Pakistan.International journal of legal medicine · 2011Article
- Southeast Asian diversity: first insights into the complex mtDNA structure of Laos.BMC evolutionary biology · 2011Article
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12 authors.
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Abstract
In order to better characterize and understand the mtDNA population genetics of Central Asia, the mtDNA control regions of over 1,500 individuals from Uzbekistan have been sequenced. Although all samples were obtained from individuals residing in Uzbekistan, individuals with direct ancestry from neighboring Central Asian countries are included. Individuals of Uzbek ancestry represent five distinct geographic regions of Uzbekistan: Fergana, Karakalpakstan, Khorezm, Qashkadarya, and Tashkent. Individuals with direct ancestry in nearby countries originate from Kazakhstan, Kyrgyzstan, Russia, Afghanistan, Turkmenistan, and Tajikistan. Our data reinforce the evidence of distinct clinal patterns that have been described among Central Asian populations with classical, mtDNA, and Y-chromosomal markers. Our data also reveal hallmarks of recent demographic events. Despite their current close geographic proximity, the populations with ancestry in neighboring countries show little sign of admixture and retain the primary mtDNA patterns of their source populations. The genetic distances and haplogroup distributions among the ethnic populations are more indicative of a broad east-west cline among their source populations than of their relatively small geographic distances from one another in Uzbekistan. Given the significant mtDNA heterogeneity detected, our results emphasize the need for heightened caution in the forensic interpretation of mtDNA data in regions as historically rich and genetically diverse as Central Asia.
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