ArticleNestle Nutrition workshop series. Paediatric programme2010
Early infancy as a critical period for development of obesity and related conditions.
Article in Nestle Nutrition workshop series. Paediatric programme, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Rapid weight gain during infancy and subsequent adiposity: a systematic review and meta-analysis of evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018Pooled it
- Effect of optimized food-based recommendations on nutrient intakes, hemoglobin levels, and memory performance of adolescent girls in East Java, Indonesia.Nutrition journal · 2025Trial
- Maternal Diet Quality and BMI as Predictors of Human Milk C-Reactive Protein Concentrations.The Journal of nutrition · 2025Article
- Effects of Crawling before Walking: Network Interactions and Longitudinal Associations in 7-Year-Old Children.International journal of environmental research and public health · 2022Article
- Associations between mothers' use of food to soothe, feeding mode, and infant weight during early infancy.Appetite · 2022Article
- Article
- Rapid infant weight gain and prenatal maternal depression are associated with prehypertension/hypertension before age 9.Journal of human hypertension · 2020Article
- Relationship between age at giving fortified powdered cow's milk and cessation of breastfeeding on the nutritional status of a Chilean child cohort followed from birth to 3 years of age.European journal of clinical nutrition · 2020Article
- Endocrine-Disrupting Chemicals and Insulin Resistance in Children.Biomedicines · 2020Review
- Weight gain in early years and subsequent body mass index trajectories across birth weight groups: a prospective longitudinal study.European journal of public health · 2020Article
- The relationship between IGF-I and -II concentrations and body composition at birth and over the first 2 months.Pediatric research · 2019Article
- Article
- Observational
- Early-Life Exposures and Risk of Diabetes Mellitus and Obesity.Current diabetes reports · 2018Review
- Impact of parental weight status on children's body mass index in early life: evidence from a Chinese cohort.BMJ open · 2018Article
- Early-life exposure to EDCs: role in childhood obesity and neurodevelopment.Nature reviews. Endocrinology · 2017Review
- Article
- Length Normalized Indices for Fat Mass and Fat-Free Mass in Preterm and Term Infants during the First Six Months of Life.Nutrients · 2016Article
- Age at Introduction to Solid Foods and Child Obesity at 6 Years.Childhood obesity (Print) · 2016Article
- Comparison of the China growth charts with the WHO growth standards in assessing malnutrition of children.BMJ open · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The current obesity epidemic has affected even the youngest children in our societies, including those in the first months of life. Animal experiments suggest that the early postnatal period may be critical to development of healthful energy homeostasis and thus prevention of obesity. In humans, observational studies and follow-up of randomized feeding trials show that rapid weight gain in the first half of infancy predicts later obesity and higher blood pressure. Despite the mounting consistency of results, several questions remain to be answered before clinical or public health implications are clear. These include the need for body composition data in infancy and data from the developing world to identify modifiable determinants of gain in adiposity in the early weeks of life, to mount interventions to modify these determinants, to examine tradeoffs of more vs. less rapid weight gain for different outcomes, and to incorporate any interventions that prove to be efficacious into clinical and public health practice in a cost-effective manner.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.