ArticleProceedings of the National Academy of Sciences of the United States of America2010
Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed.
- Early sarcopterygian morphological disparity through the Devonian-Carboniferous crisis.Scientific reports · 2025Article
- HOX-Gene Cluster Organization and Genome Duplications in Fishes and Mammals: Transcript Variant Distribution along the Anterior-Posterior Axis.International journal of molecular sciences · 2022Review
- Machine-learning of complex evolutionary signals improves classification of SNVs.NAR genomics and bioinformatics · 2022Article
- A microanatomical and histological study of the scales of the Devonian sarcopterygian Miguashaia bureaui and the evolution of the squamation in coelacanths.Journal of anatomy · 2021Article
- Giant Mesozoic coelacanths (Osteichthyes, Actinistia) reveal high body size disparity decoupled from taxic diversity.Scientific reports · 2021Article
- Article
- Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes.Human genomics · 2019Article
- Draft Genome and CompleteFrontiers in genetics · 2019Article
- Rethinking Living Fossils.Bioscience · 2018Article
- Mudskippers and Their Genetic Adaptations to an Amphibious Lifestyle.Animals : an open access journal from MDPI · 2018Review
- The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution.Nature genetics · 2018Article
- Deep time perspective on turtle neck evolution: chasing the Hox code by vertebral morphology.Scientific reports · 2017Article
- Evolutionary and Comparative Genomics to Drive Rational Drug Design, with Particular Focus on Neuropeptide Seven-Transmembrane Receptors.Biomolecules & therapeutics · 2017Review
- Functional and Comparative Genomics of Hoxa2 Gene cis-Regulatory Elements: Evidence for Evolutionary Modification of Ancestral Core Element Activity.Journal of developmental biology · 2016Article
- Hox cluster characterization of Banna caecilian (Ichthyophis bannanicus) provides hints for slow evolution of its genome.BMC genomics · 2015Article
- Genomic organisation of the seven ParaHox genes of coelacanths.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2014Article
- Interspecies insertion polymorphism analysis reveals recent activity of transposable elements in extant coelacanths.PloS one · 2014Article
- Article
- The lineage-specific evolution of aquaporin gene clusters facilitated tetrapod terrestrial adaptation.PloS one · 2014Article
- Evidence for at least six Hox clusters in the Japanese lamprey (Lethenteron japonicum).Proceedings of the National Academy of Sciences of the United States of America · 2013Article
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11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The living coelacanth is a lobe-finned fish that represents an early evolutionary departure from the lineage that led to land vertebrates, and is of extreme interest scientifically. It has changed very little in appearance from fossilized coelacanths of the Cretaceous (150 to 65 million years ago), and is often referred to as a "living fossil." An important general question is whether long-term stasis in morphological evolution is associated with stasis in genome evolution. To this end we have used targeted genome sequencing for acquiring 1,612,752 bp of high quality finished sequence encompassing the four HOX clusters of the Indonesian coelacanth Latimeria menadoensis. Detailed analyses were carried out on genomic structure, gene and repeat contents, conserved noncoding regions, and relative rates of sequence evolution in both coding and noncoding tracts. Our results demonstrate conclusively that the coelacanth HOX clusters are evolving comparatively slowly and that this taxon should serve as a viable outgroup for interpretation of the genomes of tetrapod species.
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