ArticleJournal of bacteriology2010
Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
78 citing papers in PubMed.
- Effects of Oral Administration of Goat Rumen-Derived Bacterial Isolates on In Vitro and In Vivo Rumen Fermentation Characteristics.Animals : an open access journal from MDPI · 2026Article
- Survival and Behavior of Potential Emerging Foodborne PathogenFood science & nutrition · 2026Article
- The evolving story ofFrontiers in microbiology · 2026Review
- Colorectal cancer-associatedJournal of bacteriology · 2025Article
- Current understanding of theFrontiers in veterinary science · 2025Review
- The Significance of Clinical Suspicion: From Pitting Edema to Streptococcus infantarius Endocarditis.Cureus · 2024Article
- Integration of molecular docking and molecular dynamics simulations with subtractive proteomics approach to identify the novel drug targets and their inhibitors in Streptococcus gallolyticus.Scientific reports · 2024Article
- Sciatica caused by spinal epidural abscess as the initial clinical presentation of colon cancer: a rare case report and review of literature.BMC infectious diseases · 2024Review
- Factors underlying the association betweenGut microbiome (Cambridge, England) · 2024Review
- Transcriptional control of carbohydrate catabolism by the CcpA protein in the ruminal bacteriumApplied and environmental microbiology · 2023Article
- Ruminant Salivary Microbes: Passenger or Player in the Rumen?Microorganisms · 2023Article
- Characterization of TelE, a T7SS LXG Effector Exhibiting a Conserved C-Terminal Glycine Zipper Motif Required for Toxicity.Microbiology spectrum · 2023Article
- Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.PloS one · 2023Article
- Streptococcus gallolyticus and Bacterial Endocarditis in Swine, United States, 2015-2020.Emerging infectious diseases · 2022Article
- Distribution, Diversity and Roles of CRISPR-Cas Systems in Human and Animal Pathogenic Streptococci.Frontiers in microbiology · 2022Review
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- Biochemical and Structural Characterization of a Novel Bacterial Tannase FromFrontiers in bioengineering and biotechnology · 2021Article
- Genome-Based Drug Target Identification in Human PathogenFrontiers in genetics · 2021Article
- Complete genome sequencing and comparative genome characterization of the lignocellulosic biomass degrading bacteriumBiotechnology reports (Amsterdam, Netherlands) · 2020Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Streptococcus gallolyticus (formerly known as Streptococcus bovis biotype I) is an increasing cause of endocarditis among streptococci and frequently associated with colon cancer. S. gallolyticus is part of the rumen flora but also a cause of disease in ruminants as well as in birds. Here we report the complete nucleotide sequence of strain UCN34, responsible for endocarditis in a patient also suffering from colon cancer. Analysis of the 2,239 proteins encoded by its 2,350-kb-long genome revealed unique features among streptococci, probably related to its adaptation to the rumen environment and its capacity to cause endocarditis. S. gallolyticus has the capacity to use a broad range of carbohydrates of plant origin, in particular to degrade polysaccharides derived from the plant cell wall. Its genome encodes a large repertoire of transporters and catalytic activities, like tannase, phenolic compounds decarboxylase, and bile salt hydrolase, that should contribute to the detoxification of the gut environment. Furthermore, S. gallolyticus synthesizes all 20 amino acids and more vitamins than any other sequenced Streptococcus species. Many of the genes encoding these specific functions were likely acquired by lateral gene transfer from other bacterial species present in the rumen. The surface properties of strain UCN34 may also contribute to its virulence. A polysaccharide capsule might be implicated in resistance to innate immunity defenses, and glucan mucopolysaccharides, three types of pili, and collagen binding proteins may play a role in adhesion to tissues in the course of endocarditis.
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