ReviewExperimental cell research2010
Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway.
Review in Experimental cell research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 72 citations in OpenAlex.
- Article
- Retinoic acid drives hair follicle stem cell activation via Wnt/β-catenin signalling in androgenetic alopecia.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Article
- Lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of prostate carcinogenesis.GeroScience · 2024Article
- Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer.Journal of molecular modeling · 2021Article
- Targeting of oncogenic signaling pathways by berberine for treatment of colorectal cancer.Medical oncology (Northwood, London, England) · 2020Review
- Article
- Interplay Between SOX9, Wnt/β-Catenin and Androgen Receptor Signaling in Castration-Resistant Prostate Cancer.International journal of molecular sciences · 2019Review
- Influences of Vitamin A on Vaccine Immunogenicity and Efficacy.Frontiers in immunology · 2019Article
- Revisiting the role of Wnt/β-catenin signaling in prostate cancer.Molecular and cellular endocrinology · 2018Review
- Article
- The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm.Oncotarget · 2017Article
- Article
- Loss of the vitamin D receptor in human breast and prostate cancers strongly induces cell apoptosis through downregulation of Wnt/β-catenin signaling.Bone research · 2017Article
- TCF4 Mediates the Maintenance of Neuropathic Pain Through Wnt/β-Catenin Signaling Following Peripheral Nerve Injury in Rats.Journal of molecular neuroscience : MN · 2015Article
- Dietary vitamin A regulates wingless-related MMTV integration site signaling to alter the hair cycle.Experimental biology and medicine (Maywood, N.J.) · 2015Article
- Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists.PloS one · 2015Article
- MicroRNAs and cancer stem cells: the sword and the shield.Oncogene · 2014Review
- Article
- Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling.Frontiers in genetics · 2013Review
- Motor Function Deficits Following Chronic Prenatal Ethanol Exposure are Linked to Impairments in Insulin/IGF, Notch and Wnt Signaling in the Cerebellum.Journal of diabetes & metabolism · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Predicting the potential physiological outcome(s) of any given molecular pathway is complex because of cross-talk with other pathways. This is particularly evident in the case of the nuclear hormone receptor and canonical Wnt pathways, which regulate cell growth and proliferation, differentiation, apoptosis, and metastatic potential in numerous tissues. These pathways are known to intersect at many levels: in the intracellular space, at the membrane, in the cytoplasm, and within the nucleus. The outcomes of these interactions are important in the control of stem cell differentiation and maintenance, feedback loops, and regulating oncogenic potential. The aim of this review is to demonstrate the importance of considering pathway cross-talk when predicting functional outcomes of signaling, using nuclear hormone receptor/canonical Wnt pathway cross-talk as an example.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.