ArticleVirology2010
Visualization of feline calicivirus replication in real-time with recombinant viruses engineered to express fluorescent reporter proteins.
Article in Virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Highs and Lows in Calicivirus Reverse Genetics.Viruses · 2024Review
- Impacts of Surface Characteristics and Dew Point on the Blue-Light (BLMicroorganisms · 2023Article
- A cDNA-based reverse genetics system for feline calicivirus identifies the 3' untranslated region as an essential element for viral replication.Archives of virology · 2023Article
- Positive strand RNA viruses differ in the constraints they place on the folding of their negative strand.RNA (New York, N.Y.) · 2022Article
- The Feline Calicivirus Leader of the Capsid Protein Has the Functional Characteristics of a Viroporin.Viruses · 2022Article
- Insertion of Exogenous Genes within theViruses · 2021Article
- Major Capsid Protein Synthesis from the Genomic RNA of Feline Calicivirus.Journal of virology · 2020Article
- Comparative Transcriptomic Response of Primary and Immortalized Macrophages to Murine Norovirus Infection.Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- In vitro antiviral effect of germacrone on feline calicivirus.Archives of virology · 2016Article
- Plasmid-based human norovirus reverse genetics system produces reporter-tagged progeny virus containing infectious genomic RNA.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- The feline calicivirus leader of the capsid protein is associated with cytopathic effect.Journal of virology · 2013Article
- High-resolution functional profiling of the norovirus genome.Journal of virology · 2012Article
- Polypyrimidine tract binding protein functions as a negative regulator of feline calicivirus translation.PloS one · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Caliciviruses are non-enveloped, icosahedral viruses with a single-stranded, positive sense RNA genome. Transposon-mediated insertional mutagenesis was used to insert a transprimer sequence into random sites of an infectious full-length cDNA clone of the feline calicivirus (FCV) genome. A site in the LC gene (encoding the capsid leader protein) of the FCV genome was identified that could tolerate foreign insertions, and two viable recombinant FCV variants expressing LC fused either to AcGFP, or DsRedFP were recovered. The effects of the insertions on LC processing, RNA replication, and stability of the viral genome were analyzed, and the progression of a calicivirus single infection and co-infection were captured by real-time imaging fluorescent microscopy. The ability to engineer viable recombinant caliciviruses expressing foreign markers enables new approaches to investigate virus and host cell interactions, as well as studies of viral recombination, one of the driving forces of calicivirus evolution.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.