Evidence map›Paper›PMID 20137067›Full record

ArticleBiology direct2010

FOXP3 and GARP (LRRC32): the master and its minion.

Michael Probst-Kepper, Jan Buer

Abstract read
In one paragraph

Article in Biology direct, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
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  5. Article
  6. Article
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  9. Article
  10. Article
  11. Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.Current topics in medicinal chemistry · 2016
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. The role of regulatory T cells in atopic dermatitis.Current problems in dermatology · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael Probst-KepperInstitute for Microbiology, Immunology and Hygiene, Städtisches Klinikum Braunschweig gGmbH, Braunschweig, Germany. m.probst-kepper@klinikum-braunschweig.de
Jan Buer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor FOXP3 is essential for the development and function of CD4+CD25hiFOXP3+ regulatory T (T(reg)) cells, but also expressed in activated human helper T cells without acquisition of a regulatory phenotype. This comment focuses on glycoprotein-A repetitions predominant (GARP or LRRC32) recently identified as specific marker of activated human T(reg) cells, which may provide the missing link toward a better molecular definition of the regulatory phenotype.

Indexed as

AnimalsForkhead Transcription FactorsHumansMembrane ProteinsMiceNeuropilin-1Sequence Homology, Amino AcidT-Lymphocytes, RegulatoryTransforming Growth Factor betaForkhead Transcription FactorsMembrane ProteinsNeuropilin-1Transforming Growth Factor beta

Identifiers

PMID20137067
PMCPMC2825496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.