ReviewDrugs & aging2009
Potentially inappropriate medication in elderly hospitalized patients.
Review in Drugs & aging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- Potentially inappropriate medications and regimen complexity among elderly patients in the emergency department: Insights from a pharmacist-led medication reconciliation study.Qatar medical journal · 2026Article
- Drug prescriptions in elderly hospitalized patients with cognitive impairment in the Italian Dementia Friendly Hospital project.Frontiers in pharmacology · 2024Article
- Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria.Frontiers in pharmacology · 2023Article
- Article
- Are there sex differences in potentially inappropriate prescribing in adults with multimorbidity?Journal of the American Geriatrics Society · 2021Article
- Epidemiology and associated factors of polypharmacy in older patients in primary care: a northern Italian cross-sectional study.BMC geriatrics · 2021Article
- Patient safety in marginalised groups: a narrative scoping review.International journal for equity in health · 2020Article
- Self-reported medication in community-dwelling older adults in Germany: results from the Berlin Initiative Study.BMC geriatrics · 2020Article
- Article
- Medication Safety Principles and Practice in CKD.Clinical journal of the American Society of Nephrology : CJASN · 2018Review
- Geriatric Emergency Department Innovations: Transitional Care Nurses and Hospital Use.Journal of the American Geriatrics Society · 2018Observational
- American Geriatrics Society-Beers Criteria and adverse drug reactions: a comparative cross-sectional study of Nigerian and South African older inpatients.Clinical interventions in aging · 2018Article
- Factors associated with adverse drug reactions in older inpatients in teaching hospital.International journal of clinical pharmacy · 2017Article
- Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA.BMC cardiovascular disorders · 2017Article
- Potentially inappropriate medications use in community-based aged patients: a cross-sectional study using 2012 Beers criteria.Clinical interventions in aging · 2017Observational
- Sepsis and Immunosenescence in the Elderly Patient: A Review.Frontiers in medicine · 2017Review
- Prevalence of potentially inappropriate medications and prescription cost analysis among older cardiac patients in an outpatient department of a tertiary care hospital in India.Journal of basic and clinical pharmacy · 2016Article
- Influence of Admission to a Tertiary Care Hospital after a Fall on Use of Potentially Inappropriate Medications among Older Patients.The Canadian journal of hospital pharmacy · 2014Article
- Frequency of potentially inappropriate prescriptions in older people at discharge according to Beers and STOPP criteria.International journal of clinical pharmacy · 2014Article
- Outcome of elderly patients with circulatory failure.Intensive care medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Balanced and safe prescribing is difficult to achieve in frail older adults with multiple comorbid diseases. This issue is of particular concern, especially in elderly hospitalized patients because hospitalization exposes such individuals to an increased risk of adverse drug reactions (ADRs). The avoidance of medications that are considered to be inappropriate is among the interventions for treatment options in elderly patients. A potentially inappropriate medication (PIM) is a drug in which the risk of an adverse event outweighs its clinical benefit, particularly when there is a safer or more effective alternative therapy for the same condition. Explicit criteria have been developed to identify PIMs and among these, Beers' criteria are the most frequently applied in the literature. However, evidence suggests that such criteria cannot easily be applied to elderly hospitalized people in European countries; approximately 20% of drugs listed in Beers' criteria are rarely prescribed or are not available in Europe, and Beers' listed PIMs are not associated with inhospital mortality, length of hospital stay and/or ADRs in Italian studies. On the contrary, ADRs can contribute to accelerated functional decline in elderly hospitalized patients independently of the use of Beers' listed PIMs. Therefore, we will review the evidence pertaining to the application of Beers' criteria in elderly hospitalized patients, while focusing on Italian studies that have investigated the role of PIMs as potential predictors of negative hospital outcomes. In addition, we will also review the available evidence regarding new European criteria on identifying PIMs, because clinical application in elderly hospitalized Europeans is still under investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.