ReviewWorld journal of gastroenterology2010
How useful is rectal endosonography in the staging of rectal cancer?
Review in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01437514 (the Effect of the Preoperative Short-course Radiotherapy for the cT3/cN+ Mid-lower Rectal Cancer), which is not on this map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
the Effect of the Preoperative Short-course Radiotherapy for the cT3/cN+ Mid-lower Rectal Cancer: a Prospective Randomized Study
Who cites it
27 citing papers in PubMed, 63 citations in OpenAlex.
- Clinical results and toxicity for short-course preoperative radiotherapy and total mesorectal excision in rectal cancer patients.Journal of radiation research · 2015Trial
- Endorectal Ultrasound Versus MRI for Lower and Middle Rectal Cancer Staging in Upfront Surgery: A Comparative Study.Journal of clinical medicine · 2026Article
- Chinese clinical practice guidelines for super minimally invasive surgery of digestive tract tumors.Journal of translational internal medicine · 2025Article
- Ultrasound assessment of low type intersphincteric perianal fistulas in Yemen.Scientific reports · 2025Article
- Endorectal ultrasound with elastography for differentiating benign and malignant rectal tumors: a systematic review and meta-analysis.American journal of translational research · 2025Review
- Current update on the role of endoanal ultrasound: a primer for radiologists.Abdominal radiology (New York) · 2024Review
- Article
- Endoluminal ultrasound versus magnetic resonance imaging in assessment of rectal cancer after neoadjuvant therapy.BMC gastroenterology · 2022Article
- Endorectal ultrasound radiomics in locally advanced rectal cancer patients: despeckling and radiotherapy response prediction using machine learning.Abdominal radiology (New York) · 2022Article
- Practical approach to linear endoscopic ultrasound examination of the rectum and anal canal.Endoscopy international open · 2022Review
- Review
- Clinical benefits of oral capecitabine over intravenous 5-fluorouracyl regimen in case of neoadjuvant chemoradiotherapy followed by surgery for locally advanced rectal cancer.Pathology oncology research : POR · 2022Article
- Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach.Journal of clinical medicine · 2021Article
- Preoperative prediction of tumour deposits in rectal cancer by an artificial neural network-based US radiomics model.European radiology · 2020Article
- EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound.Ultrasound international open · 2019Review
- The Optimal Application of Transrectal Ultrasound in Staging of Rectal Cancer Following Neoadjuvant Therapy: A Pragmatic Study for Accuracy Investigation.Journal of Cancer · 2018Article
- Role of ultrasound in colorectal diseases.World journal of gastroenterology · 2016Review
- Rectal Tumour Staging with Endorectal Ultrasound: Is There Any Difference between Western and Eastern European Countries?Gastroenterology research and practice · 2016Article
- The accuracy of endorectal ultrasonography in rectal cancer staging.Clujul medical (1957) · 2015Article
- Transrectal ultrasonography of anorectal diseases: advantages and disadvantages.Ultrasonography (Seoul, Korea) · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is essential in treating rectal cancer to have adequate preoperative imaging, as accurate staging can influence the management strategy, type of resection, and candidacy for neoadjuvant therapy. In the last twenty years, endorectal ultrasound (ERUS) has become the primary method for locoregional staging of rectal cancer. ERUS is the most accurate modality for assessing local depth of invasion of rectal carcinoma into the rectal wall layers (T stage). Lower accuracy for T2 tumors is commonly reported, which could lead to sonographic overstaging of T3 tumors following preoperative therapy. Unfortunately, ERUS is not as good for predicting nodal metastases as it is for tumor depth, which could be related to the unclear definition of nodal metastases. The use of multiple criteria might improve accuracy. Failure to evaluate nodal status could lead to inadequate surgical resection. ERUS can accurately distinguish early cancers from advanced ones, with a high detection rate of residual carcinoma in the rectal wall. ERUS is also useful for detection of local recurrence at the anastomosis site, which might require fine-needle aspiration of the tissue. Overstaging is more frequent than understaging, mostly due to inflammatory changes. Limitations of ERUS are operator and experience dependency, limited tolerance of patients, and limited range of depth of the transducer. The ERUS technique requires a learning curve for orientation and identification of images and planes. With sufficient time and effort, quality and accuracy of the ERUS procedure could be improved.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.