ReviewImmunologic research2010
Mechanisms involved in antibody- and complement-mediated allograft rejection.
Review in Immunologic research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Complement in Antibody-Mediated Rejection of the Kidney Graft: From Pathophysiology to Clinical Practice.Journal of clinical medicine · 2025Review
- Dynamic Neutrophil Subsets and Function in Lung Transplant Recipients: Insights from a One-Year Longitudinal Pilot Study.Journal of clinical medicine · 2025Article
- Ablation of FAS confers allogeneic CD3Nature biomedical engineering · 2024Article
- The Effects of IL-23/IL-18-Polarized Neutrophils on Renal Ischemia-Reperfusion Injury and Allogeneic-Skin-Graft Rejection in Mice.Biomedicines · 2023Article
- TLR7 Activation Accelerates Cardiovascular Pathology in a Mouse Model of Lupus.Frontiers in immunology · 2022Article
- Molecular Assessment of C4d-Positive Renal Transplant Biopsies Without Evidence of Rejection.Kidney international reports · 2019Article
- Non-canonical activity of the podosomal formin FMNL1γ supports immune cell migration.Journal of cell science · 2017Article
- The Role of Neutrophils in Transplanted Organs.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2017Review
- The Effect of Tacrolimus and Mycophenolic Acid on CD14+ Monocyte Activation and Function.PloS one · 2017Article
- The Impact of HLA Class I-Specific Killer Cell Immunoglobulin-Like Receptors on Antibody-Dependent Natural Killer Cell-Mediated Cytotoxicity and Organ Allograft Rejection.Frontiers in immunology · 2016Review
- Tolerogenic Dendritic Cells on Transplantation: Immunotherapy Based on Second Signal Blockage.Journal of immunology research · 2015Review
- Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation.PloS one · 2015Article
- Sensitive solid-phase detection of donor-specific antibodies as an aid highly relevant to improving allograft outcomes.Molecular diagnosis & therapy · 2014Review
- Immune-mediated vascular injury and dysfunction in transplant arteriosclerosis.Frontiers in immunology · 2014Review
- Inhibition of the classical and lectin pathway of the complement system by recombinant LAIR-2.Journal of innate immunity · 2014Article
- Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation.Respiratory research · 2012Article
- Regulatory T cell-mediated control of autoantibody-induced inflammation.Frontiers in immunology · 2012Article
- Antibody-mediated rejection: an evolving entity in heart transplantation.Journal of transplantation · 2012Article
- Article
- Novel functions of B cells in transplantation.Current opinion in organ transplantation · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Antibody-mediated rejection has become critical clinically because this form of rejection is usually unresponsive to conventional anti-rejection therapy, and therefore, it has been recognized as a major cause of allograft loss. Our group developed experimental animal models of vascularized organ transplantation to study pathogenesis of antibody- and complement-mediated endothelial cell injury leading to graft rejection. In this review, we discuss mechanisms of antibody-mediated graft rejection resulting from activation of complement by C1q- and MBL (mannose-binding lectin)-dependent pathways and interactions with a variety of effector cells, including macrophages and monocytes through Fcgamma receptors and complement receptors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.