Trial reportSurgical endoscopy2010
A prospective randomized trial comparing two-stage versus single-stage management of patients with gallstone disease and common bile duct stones.
Trial report in Surgical endoscopy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 41 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Long Term Comparison of Laparoscopic Common Bile Duct Exploration and Cholecystectomy Versus Sequential ERCP Followed by Cholecystectomy for Choledocholithiasis: a Multicenter Prospected Non-randomized Controlled Study
preGallstep: One-step Laparoscopic Cholecystectomy, Common Bile Duct Exploration and Stone Extraction Versus Two-step Endoscopic Retrograde Cholangiography and Stone Extraction Plus Laparoscopic Cholecystectomy for Common Bile Duct Stones
Who cites it
41 citing papers in PubMed, 12 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Minimally invasive surgical strategies for gallbladder stones with concomitant common bile duct stones: a systematic review and network meta-analysis.BMC surgery · 2026Pooled it
- Safety and efficacy comparison of single-stage and two-stage ERCP combined with laparoscopic cholecystectomy: a meta-analysis and systematic review.Frontiers in medicine · 2025Pooled it
- EAES rapid guideline: updated systematic review, network meta-analysis, CINeMA and GRADE assessment, and evidence-informed European recommendations on the management of common bile duct stones.Surgical endoscopy · 2022Guideline
- Laparoscopic common bile duct exploration plus cholecystectomy versus endoscopic retrograde cholangiopancreatography plus laparoscopic cholecystectomy for cholecystocholedocholithiasis: a meta-analysis.Surgical endoscopy · 2019Pooled it
- Pooled it
- Pooled it
- Pooled it
- One-stage laproendoscopic procedure versus two-stage procedure in the management for gallstone disease and biliary duct calculi: a systemic review and meta-analysis.Surgical endoscopy · 2016Pooled it
- Transcystic or transductal stone extraction during single-stage treatment of choledochocystolithiasis: a systematic review.World journal of surgery · 2014Pooled it
- Surgical versus endoscopic treatment of bile duct stones.The Cochrane database of systematic reviews · 2013Pooled it
- Two-stage vs single-stage management for concomitant gallstones and common bile duct stones.World journal of gastroenterology · 2012Pooled it
- Meta-analysis of one- vs. two-stage laparoscopic/endoscopic management of common bile duct stones.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2012Pooled it
- Two institutes' experience in laparoendoscopic "rendezvous" technique for patients undergoing laparoscopic cholecystectomy for stones in the gallbladder and bile duct: a prospective randomized comparative clinical trial.Updates in surgery · 2024Trial
- Single-stage vs. two-stage management for concomitant gallstones and common bile duct stones: a prospective randomized trial with long-term follow-up.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2014Trial
- Trial
- Transcystic and choledochotomy approaches of laparoscopic bile duct exploration show distinct outcomes against ERCP + laparoscopic cholecystectomy in a meta-analysis of randomised controlled trials.Updates in surgery · 2026Article
- Historical perspectives on choledocholithiasis: the pioneering contribution of Dr. George Berci.Surgical endoscopy · 2026Article
- Management of multiple common bile duct stones via laparoscopic transcholedochal exploration: an observational study.Frontiers in surgery · 2026Article
- Treatment for recurrent choledocholithiasis: endoscopic? or laparoscopic? A prospective cohort study.Surgical endoscopy · 2025Article
- Structured learning and mentoring: shortening the learning curve in laparoscopic common bile duct exploration.Surgical endoscopy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal management of patients with concomitant common bile duct stones and gallstones is still evolving. With the introduction of laparoscopic common bile duct exploration, many centers prefer single-stage laparoscopic cholecystectomy and common bile duct exploration over preoperative endoscopic bile duct clearance followed by laparoscopic cholecystectomy. The present study was done to compare these two management options. PATIENTS AND
methods30 patients with symptomatic gallstones and common bile duct stones were randomized to either treatment option. Preoperative endoscopic ultrasound (EUS) and/or magnetic resonance pancreaticography (MRCP) was done in all patients to confirm the diagnosis. In group I, laparoscopic cholecystectomy and common bile duct exploration was done at the same sitting; in group II, endoscopic stone clearance was followed by laparoscopic cholecystectomy 4-6 weeks later. Success was defined as successful treatment by the intended modality.
results15 patients were randomized to each group and the two groups had comparable demographic and clinical profile. In group I there was a success rate of 93.5% in comparison with 86.7% in group II (p = 0.32, Fisher's exact test). The complications were similar in the two groups.
conclusionsThe results showed equivalent success rate in terms of morbidity and hospital stay. Laparoscopic approach seems to be favorable because of the smaller number of procedures and hospital visits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.