Evidence map›Paper›PMID 20134029›Full record

ArticleBioinformatics (Oxford, England)2010

Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning.

Chia-Chin Wu, Shahab Asgharzadeh, Timothy J Triche, David Z D'Argenio

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. MoNETA: MultiOmics Network Embedding for SubType Analysis.NAR genomics and bioinformatics · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Systems genetics in "-omics" era: current and future development.Theory in biosciences = Theorie in den Biowissenschaften · 2013
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chia-Chin WuDepartment of Biomedical Engineering, University of Southern California, Los Angeles, 90089, USA.
Shahab Asgharzadeh
Timothy J Triche
David Z D'Argenio

Funding

TrainingP41EB001978 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KHOO, MICHAEL C K · 2003 to 2017
$18.1M
CLINICAL CORRELATIVE STUDIES OF NEUROBLASTOMAR01CA060104 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI SEEGER, ROBERT CHARLES · 1998 to 2010
$5.3M
CLINICAL CORRELATIVE STUDIES OF NEUROBLASTOMAU01CA060104 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI SEEGER, ROBERT C · 1993 to 1996
–
NCI NIH HHS K12-CA60104NIBIB NIH HHS P41 EB001978NIBIB NIH HHS P41-EB001978
6 · The paper itself

Abstract

motivationThree major problems confront the construction of a human genetic network from heterogeneous genomics data using kernel-based approaches: definition of a robust gold-standard negative set, large-scale learning and massive missing data values.

resultsThe proposed graph-based approach generates a robust GSN for the training process of genetic network construction. The RVM-based ensemble model that combines AdaBoost and reduced-feature yields improved performance on large-scale learning problems with massive missing values in comparison to Naïve Bayes. CONTACT: dargenio@bmsr.usc.edu SUPPLEMENTARY INFORMATION: Supplementary material is available at Bioinformatics online.

Indexed as

Databases, FactualGenomicsHumansSignal Transduction

Identifiers

PMID20134029
PMCPMC2832827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.