Evidence map›Paper›PMID 20133564›Full record

ReviewScience (New York, N.Y.)2010

Development of monocytes, macrophages, and dendritic cells.

Frederic Geissmann, Markus G Manz, Steffen Jung, Michael H Sieweke, Miriam Merad, Klaus Ley

Erratum issuedAbstract readReview
In one paragraph

Review in Science (New York, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1,507 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,507citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,507 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Changes in leukocytes and CRP in different treatments of major depression.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. CD44-Hyaluronan-Dependent Monocyte Rolling.International journal of molecular sciences · 2026
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review

1,447 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

6 authors.

Frederic GeissmannCentre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection, and Inflammatory Diseases, King's College London, Great Maze Pond, London SE1 1UL, UK. frederic.geissmann@kcl.ac.uk
Markus G Manz
Steffen Jung
Michael H Sieweke
Miriam Merad
Klaus Ley

Funding

MONOCYTE ADHESION TO ATHEROMA IN GENE TARGETED MICER01HL058108 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LEY, KLAUS F. · 1997 to 2009
$2.6M
Medical Research Council G0900867NHLBI NIH HHS R01 HL058108
6 · The paper itself

Abstract

Monocytes and macrophages are critical effectors and regulators of inflammation and the innate immune response, the immediate arm of the immune system. Dendritic cells initiate and regulate the highly pathogen-specific adaptive immune responses and are central to the development of immunologic memory and tolerance. Recent in vivo experimental approaches in the mouse have unveiled new aspects of the developmental and lineage relationships among these cell populations. Despite this, the origin and differentiation cues for many tissue macrophages, monocytes, and dendritic cell subsets in mice, and the corresponding cell populations in humans, remain to be elucidated.

Indexed as

MyelopoiesisAnimalsCell LineageCell ProliferationCytokinesDendritic CellsHomeostasisHumansInflammationMacrophagesMiceMonocytesMyeloid Progenitor CellsPhagocytosisTranscription, GeneticCytokines

Identifiers

PMID20133564
PMCPMC2887389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.