ReviewJournal of applied physiology (Bethesda, Md. : 1985)2010
Central chemoreception in wakefulness and sleep: evidence for a distributed network and a role for orexin.
Review in Journal of applied physiology (Bethesda, Md. : 1985), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 77 citations in OpenAlex.
- Absence of pharmacokinetic and pharmacodynamic interactions between almorexant and warfarin in healthy subjects.Drugs in R&D · 2013Trial
- Galaninergic and hypercapnia-activated neuronal projections to the ventral respiratory column.Brain structure & function · 2024Article
- Exaggerated postnatal surge of orexin neurons and the effects of elimination of excess orexin on blood pressure and exaggerated chemoreflex in spontaneously hypertensive rats.Frontiers in physiology · 2024Article
- Chronic moderate hypercapnia suppresses ventilatory responses to acute CO<sub>2</sub> challenges.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- The OFrontiers in physiology · 2022Review
- Influence of light/dark cycle and orexins on breathing control in green iguanas (Iguana iguana).Scientific reports · 2020Article
- Impact of inflammation on developing respiratory control networks: rhythm generation, chemoreception and plasticity.Respiratory physiology & neurobiology · 2020Review
- Hypercapnia-induced active expiration increases in sleep and enhances ventilation in unanaesthetized rats.The Journal of physiology · 2018Article
- Impaired chemosensory control of breathing after depletion of bulbospinal catecholaminergic neurons in rats.Pflugers Archiv : European journal of physiology · 2018Article
- Orexinergic system in the locus coeruleus modulates the CO2 ventilatory response.Pflugers Archiv : European journal of physiology · 2016Article
- Behavioral, Ventilatory and Thermoregulatory Responses to Hypercapnia and Hypoxia in the Wistar Audiogenic Rat (WAR) Strain.PloS one · 2016Article
- The retrotrapezoid nucleus stimulates breathing by releasing glutamate in adult conscious mice.The European journal of neuroscience · 2015Article
- Regulation of breathing and autonomic outflows by chemoreceptors.Comprehensive Physiology · 2014Review
- Chemoreception and asphyxia-induced arousal.Respiratory physiology & neurobiology · 2013Review
- Lateral hypothalamus as a sensor-regulator in respiratory and metabolic control.Physiology & behavior · 2013Review
- Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats.Hypertension (Dallas, Tex. : 1979) · 2013Article
- Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- State-dependent modulation of breathing in urethane-anesthetized rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
- Respiratory regulation in narcolepsy.Sleep & breathing = Schlaf & Atmung · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This minireview examines data showing the locations of central chemoreceptor sites as identified by the presence of ventilatory responses to focal, mild acidification produced in unanesthetized animals in vivo, how the site-specific responses vary by arousal state, and what the emerging role of orexin might be in this state-dependent central chemoreceptor system. We comment on the organization of this distributed central chemoreceptor system and suggest that interactions among sites are synergistic and not additive, which is an important aspect of its normal function.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.