ArticleNeuroscience letters2010
Developmental and genetic influences on prefrontal function in adolescents: a longitudinal twin study of WCST performance.
Article in Neuroscience letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Effects of sertraline on executive function and quality of life in patients with advanced cancer.Medical science monitor : international medical journal of experimental and clinical research · 2014Trial
- Psychometrics of drift-diffusion model parameters derived from the Eriksen flanker task: Reliability and validity in two independent samples.Cognitive, affective & behavioral neuroscience · 2025Article
- Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective.Developmental cognitive neuroscience · 2025Article
- The roles of familial transmission and smoking during pregnancy on executive function skills: A sibling-comparison study.Development and psychopathology · 2022Article
- Set Shifting and Inhibition Deficits as Potential Endophenotypes for Depression.Psychiatry research · 2021Article
- Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth.Development and psychopathology · 2021Article
- Attentional set shifting in HAP3, LAP3, and cHAP mice is unaffected by either genetic differences in alcohol preference or an alcohol drinking history.Experimental and clinical psychopharmacology · 2020Article
- The relationship between facial emotion recognition and executive functions in first-episode patients with schizophrenia and their siblings.BMC psychiatry · 2015Article
- Neural correlates of inhibitory control and functional genetic variation in the dopamine D4 receptor gene.Neuropsychologia · 2014Article
- Interindividual differences in mid-adolescents in error monitoring and post-error adjustment.PloS one · 2014Article
- The genetic and environmental etiology of decision-making: a longitudinal twin study.Journal of adolescence · 2013Article
- Phenotypic and genetic analyses of the Wisconsin Card Sort.Behavior genetics · 2012Article
- Cognitive functions in ataxia with oculomotor apraxia type 2.Frontiers in neurology · 2012Article
- A three-year longitudinal functional magnetic resonance imaging study of performance monitoring and test-retest reliability from childhood to early adulthood.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
Corrections and comments
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4 authors.
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Abstract
Adolescence is characterized by a relative immaturity of the prefrontal cortex and associated cognitive control functions, which is hypothesized to be a major contributing factor to high-risk behaviors. However, little is known about the role of genetic and environmental factors in frontal brain development during adolescence. Here we examined heritability of performance on the Wisconsin Card Sorting Test (WCST), an established neuropsychological measure of prefrontally mediated executive functioning, in a longitudinal sample of adolescent twins (n=747) tested at ages 12 and 14. WSCT performance significant improved with age as indicated by a decrease in the number of perseverative errors (p<0.001), which was paralleled by an increase in heritability in females (19% at age 12 and 49% at age 14) and shared environmental influences in males (non-significant at age 12 and 34% at age 14). The results suggest increasing influence of familial factors on frontal executive functioning during adolescence, as well as gender differences in the relative role of genetic and environmental factors.
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