Evidence map›Paper›PMID 20131086›Full record

ReviewJournal of mammary gland biology and neoplasia2010

The role of histone modifications and variants in regulating gene expression in breast cancer.

Mathieu Dalvai, Kerstin Bystricky

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mathieu DalvaiUniversité de Toulouse, LBME, 118 route de Narbonne, 31062, Toulouse, France. mathieu.dalvai@ibcg.biotoul.fr
Kerstin Bystricky

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of epigenetic phenomena in cancer biology is increasingly being recognized. Here we focus on the mechanisms and enzymes involved in regulating histone methylation and acetylation, and the modulation of histone variant expression and deposition. Implications of these epigenetic marks for tumor development, progression and invasiveness are discussed with a particular emphasis on breast cancer progression.

Indexed as

Epigenesis, GeneticGene Expression Regulation, NeoplasticAcetylationAnimalsBreast NeoplasmsFemaleGenetic VariationHistone AcetyltransferasesHistone DeacetylasesHistone DemethylasesHistone-Lysine N-MethyltransferaseHistonesHumansIsoenzymesMethylationProtein-Arginine N-MethyltransferasesHistone AcetyltransferasesHistone DeacetylasesHistone DemethylasesHistone-Lysine N-MethyltransferaseHistonesIsoenzymesProtein-Arginine N-Methyltransferases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.