Evidence map›Paper›PMID 20131036›Full record

ArticleChinese journal of integrative medicine2010

The effect of Xuefu Zhuyu Decoction on in vitro endothelial progenitor cell tube formation.

Dong Gao, Li-ya Wu, Yu-huan Jiao, Wen-yuan Chen, Yan Chen, Ted J Kaptchuk, Bo Lu, Jun Song, Ke-ji Chen

Open access · greenAbstract read
In one paragraph

Article in Chinese journal of integrative medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Combination ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  7. Article
  8. African journal of traditional, complementary, and alternative medicines : AJTCAM · 2017
    Article
  9. Article
  10. Chinese medicines and bioactive compounds for treatment of stroke.Chinese journal of integrative medicine · 2015
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Dong GaoDepartment of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, China.
Li-ya Wu
Yu-huan Jiao
Wen-yuan Chen
Yan Chen
Ted J Kaptchuk
Bo Lu
Jun Song
Ke-ji Chen
China Academy of Chinese Medical Sciences · CNFujian University of Traditional Chinese Medicine · CNHarvard University · US

Funding

Mentoring and Research in Placebo Studies, Asian Medicine, and CAMK24AT004095 · NCCIH · HARVARD MEDICAL SCHOOL · PI KAPTCHUK, TED · 2007 to 2016
$1.4M
NCCIH NIH HHS K24 AT004095
6 · The paper itself

Abstract

objectiveTo observe the effect of Xuefu Zhuyu Decoction ()-containing serum (XFZYD-CS) on endothelial progenitor cell (EPC) tube formation in vitro.

methodsMononuclear cells from rat bone marrow were prepared in a Ficoll density gradient centrifuge. EPCs were separated by the differential attachment method, and observed with inverted microscope for the effect of XFZYD-CS on EPC tube formation.

resultsAfter one day, EPCs exposed to the serum containing 5%, 10% and 15% XFZYD-CS formed typical tubes or vessel networks. The tube formation time was two days ahead of the control group and the size of most tubes in the serum groups was smaller than in the control group.

conclusionXFZYD-CS could induce EPC angiogenesis and hasten tube formation, especially in capillary vessels. The study provides experimental evidence for the plausibility of Xuefu Zhuyu Decoction in the treatment of ischemic diseases.

Indexed as

Angiogenesis Inducing AgentsAnimalsCell DifferentiationCells, CulturedCell ShapeDrug Evaluation, PreclinicalDrugs, Chinese HerbalEndothelial CellsNeovascularization, PhysiologicRatsRats, Sprague-DawleyStem CellsAngiogenesis Inducing AgentsDrugs, Chinese HerbalXue-Fu-Zhu-Yu decoction

Identifiers

PMID20131036
PMCPMC2819674
OpenAlexW35416211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.