ArticleBioorganic & medicinal chemistry2010
Synthesis and carbohydrate binding studies of fluorescent alpha-amidoboronic acids and the corresponding bisboronic acids.
Article in Bioorganic & medicinal chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 33 citations in OpenAlex.
- Cobalt-Catalyzed Enantioselective Hydroboration of α-Substituted Acrylates.Journal of the American Chemical Society · 2024Article
- Synthetic lectin arrays for the detection and discrimination of cancer associated glycans and cell lines.Chemical science · 2012Article
- Click reactions and boronic acids: applications, issues, and potential solutions.Molecules (Basel, Switzerland) · 2010Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
Fluorescent boronic acids are very useful for the design and synthesis of carbohydrate sensors. In an earlier communication, we first described the effort of developing water soluble fluorescent alpha-amidoboronic acids, which change fluorescence upon sugar binding. In this report, we describe a general method of functionalizing such boronic acids and their applications in the preparation of bis-alpha-amidoboronic acids with significantly enhanced binding for oligosaccharides as compared to their monoboronic acid counterparts. The advantages of good water solubility, easy modification to generate diversity, and modularity in synthesis will make alpha-amidoboronic acids very useful building blocks for future synthesis of boronic acid-based fluorescent sensors.
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Registered trials
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