ArticleThe Plant journal : for cell and molecular biology2010
ASKtheta, a group-III Arabidopsis GSK3, functions in the brassinosteroid signalling pathway.
Article in The Plant journal : for cell and molecular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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62 citing papers in PubMed.
- Omics-based characterization of physiological and transcriptomic resilience during cold de-acclimation and re-acclimation in GSK-like kinase mutants.BMC plant biology · 2026Article
- Brassinosteroids control cell proliferation in the lateral root cap of the Arabidopsis root.EMBO reports · 2026Article
- The maize GSK3-like kinase ZmSK1 negatively regulates drought tolerance by phosphorylating the transcription factor ZmCPP2.The Plant cell · 2025Article
- Brassinosteroid biosynthesis and signaling: Conserved and diversified functions of core genes across multiple plant species.Plant communications · 2024Review
- GmBES1-1 dampens the activity of GmNSP1/2 to mediate brassinosteroid inhibition of nodulation in soybean.Plant communications · 2023Article
- Regulatory network of GSK3-like kinases and their role in plant stress response.Frontiers in plant science · 2023Review
- Behavior and possible function ofPlant signaling & behavior · 2022Article
- Genome-Wide Characterization and Phylogenetic Analysis of GSK Genes in Maize and Elucidation of Their General Role in Interaction with BZR1.International journal of molecular sciences · 2022Article
- Brassinosteroid-regulated bHLH transcription factor CESTA induces the gibberellin 2-oxidase GA2ox7.Plant physiology · 2022Article
- Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Transcription factor BES1 interacts with HSFA1 to promote heat stress resistance of plants.The EMBO journal · 2022Article
- SlCESTA Is a Brassinosteroid-Regulated bHLH Transcription Factor of Tomato That Promotes Chilling Tolerance and Fruit Growth When Over-Expressed.Frontiers in plant science · 2022Article
- Glycogen synthase kinases in model and crop plants - From negative regulators of brassinosteroid signaling to multifaceted hubs of various signaling pathways and modulators of plant reproduction and yield.Frontiers in plant science · 2022Review
- Review
- Early transcriptome changes induced by the Geminivirus C4 oncoprotein: setting the stage for oncogenesis.BMC genomics · 2021Article
- Brassinosteroid Signaling, Crosstalk and, Physiological Functions in Plants Under Heavy Metal Stress.Frontiers in plant science · 2021Review
- Comparative phosphoproteomic analysis of BR-defective mutant reveals a key role of GhSK13 in regulating cotton fiber development.Science China. Life sciences · 2020Article
- Two chloroplast thioredoxin systems differentially modulate photosynthesis in Arabidopsis depending on light intensity and leaf age.The Plant journal : for cell and molecular biology · 2020Article
- AMP1 and CYP78A5/7 act through a common pathway to govern cell fate maintenance in Arabidopsis thaliana.PLoS genetics · 2020Article
- Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation.Molecular systems biology · 2020Article
2 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Brassinosteroids (BRs) are plant hormones that regulate many processes including cell elongation, leaf development, pollen tube growth and xylem differentiation. GSK3/shaggy-like kinases (GSK) are critical regulators of intracellular signalling initiated by the binding of BR to the BRI1 receptor complex. Three GSKs have already been shown to relay BR responses, including phosphorylation of the transcriptional regulator BES1. However, recent studies indicate that one or more yet unidentified protein kinases are involved in BR signalling. Here, we show that the in vivo protein kinase activity of the group-III GSK, ASKtheta, was negatively regulated by BRI1. Arabidopsis thaliana plants with enhanced ASKtheta activity displayed a bri1-like phenotype. ASKtheta overexpressors accumulated high levels of brassinolide, castasterone and typhasterol, and were insensitive to BR. ASKtheta localized to the nucleus and directly phosphorylated BES1 and BZR1. Moreover, the BES1/BZR1-like transcription factor BEH2 was isolated as an ASKtheta interaction partner in a yeast two-hybrid screen. ASKtheta phosphorylated BEH2 both in vitro and in vivo. Overall, these data provide strong evidence that ASKtheta is a novel component of the BR signalling cascade, targeting the transcription factors BES1, BZR1 and BEH2.
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