ArticleJournal of thrombosis and haemostasis : JTH2010
Incidence and risk factors for pulmonary embolism in the postpartum period.
Article in Journal of thrombosis and haemostasis : JTH, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Venous Thromboembolism Prophylaxis Post Cesarean Section(PRO-CS-Trial)
Thromboelastography to Assess Age-Related Coagulation Differences in Patients Undergoing Elective Cesarean Delivery.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- Pre-Existing and Gestational Diabetes and Risk of Maternal Venous Thromboembolism: A Systematic Review and Meta-Analysis of Observational Studies.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Sex as a prognostic factor for mortality in adults with acute symptomatic pulmonary embolism.The Cochrane database of systematic reviews · 2025Pooled it
- Evaluation of Systemic Inflammatory Indices in Pregnant Women With Deep Vein Thrombosis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- Construction of nursing-sensitive quality indicators for pregnancy-associated venous thromboembolism using the Delphi method.BMC nursing · 2026Article
- Management of Catastrophic Postpartum Acute Pulmonary Embolism With Extracorporeal Membrane Oxygenation Support and Thromboaspiration: A Case Report.Case reports in obstetrics and gynecology · 2026Article
- Amniotic fluid embolism complicated by pulmonary embolism leading to multiple organ dysfunction: case report.Frontiers in medicine · 2026Article
- Pulmonary Embolism in Women in the Era of Expanding Advanced Therapies.Current cardiology reports · 2025Review
- A comparison of international clinical practice guidelines for postpartum venous thromboembolism prophylaxis.BMC pregnancy and childbirth · 2025Article
- Low-molecular-weight heparins utilization in pregnant and postpartum women: a real-world analysis in China (2016-2021).Frontiers in pharmacology · 2025Article
- Risk Factors and Outcomes of Acute Pulmonary Embolism in African Patients: A Systematic Review.Cureus · 2024Review
- Atrial fibrillation considerations in the fourth trimester (postpartum period).Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Review
- A Comprehensive Review of Risk Factors and Thrombophilia Evaluation in Venous Thromboembolism.Journal of clinical medicine · 2024Review
- Excluding pregnancy-associated deep vein thrombosis with whole-leg ultrasound.Research and practice in thrombosis and haemostasis · 2023Article
- High rates of venous thromboembolism among deliveries complicated by cancer.Journal of thrombosis and haemostasis : JTH · 2023Article
- Venous Thromboembolism in Pregnancy: Challenges and Solutions.Vascular health and risk management · 2023Review
- Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study.Critical care (London, England) · 2022Article
- Case report: Depressive disorder with peripartum onset camouflages suspected intracranial tuberculoma.Frontiers in psychiatry · 2022Article
- The Risk of Thrombosis Around Pregnancy: Where Do We Stand?Frontiers in cardiovascular medicine · 2022Article
- Acute Pulmonary Embolism During Pregnancy and Puerperium: National Trends and In-Hospital Outcomes.Mayo Clinic proceedings · 2021Article
- Diseases and complications of the puerperium.Deutsches Arzteblatt international · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SUMMARY
backgroundPregnancy and the postpartum period are times of hypercoagulability, increasing the risk of pulmonary embolism. Better quantification of risk factors can help target women who are most likely to benefit from postpartum thromboprophylaxis with heparin.
objectivesTo determine the incidence rate and timing of postpartum pulmonary embolism, and assess perinatal risk factors predictive of the event. PATIENTS/
methodsAntenatal, delivery and postpartum admission records of a cohort of 510 889 pregnancies were analysed. Pulmonary embolism was identified from ICD-10 codes at delivery, transfer or upon readmission at any time in the postpartum period.
resultsPulmonary embolism occurred in 375 women and was most common postpartum. The rate of postpartum pulmonary embolism without an antecedent thrombotic event was 0.45 per 1000 births. By the end of 4 weeks postpartum, the weekly rate approached the background rate of pulmonary embolism in the population. Although the Caesarean section rate rose significantly throughout the study period, and pulmonary embolism was more common following abdominal birth, the rate of pulmonary embolism following Caesarean birth fell. Regression modelling demonstrated that stillbirth (adjusted odds ratio [aOR] =5.97), lupus (aOR = 8.83) and transfusion of a coagulation product (aOR = 8.84) were most strongly associated with pulmonary embolism postpartum.
conclusionsPulmonary embolism most commonly occurs up to 4 weeks postpartum and following abdominal birth. Despite this the absolute event rate is low and a broadly inclusive risk factor approach to the use of pharmacological thromboprophylaxis will require many women to be exposed to heparin to prevent an embolic event.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.