ArticleInflammatory bowel diseases2010
Final adult height of children with inflammatory bowel disease is predicted by parental height and patient minimum height Z-score.
Article in Inflammatory bowel diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Nutritional Status, Body Composition and Growth in Paediatric-Onset Ulcerative Colitis: A Systematic Review.Nutrients · 2026Pooled it
- Meta-analysis of sample-level dbGaP data reveals novel shared genetic link between body height and Crohn's disease.Human genetics · 2021Pooled it
- [Nutritional impact of inflammatory bowel diseases on children and adolescents].Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2014Pooled it
- Exclusive enteral nutrition induces early clinical, mucosal and transmural remission in paediatric Crohn's disease.Journal of gastroenterology · 2014Trial
- Effect of inhaled glucocorticoids in childhood on adult height.The New England journal of medicine · 2012Trial
- Nutritional Approach in Pediatric Patients with Inflammatory Bowel Disease: Treatment, Risk and Challenges.Nutrients · 2025Review
- Tanner's target height formula underestimates final adult height in Korean adolescents and young adults: reassessment of target height based on the Korean National Health and Nutrition Examination Survey 2010-2019.BMJ paediatrics open · 2024Article
- Factors Associated with Reaching Mid-Parental Height in Patients Diagnosed with Inflammatory Bowel Disease in Childhood and Adolescent Period.Gut and liver · 2024Observational
- Nutritional characteristic of children with inflammatory bowel disease in the nationwide inflammatory bowel disease registry from the Mediterranean region.European journal of clinical nutrition · 2022Article
- Dietary Management in Pediatric Patients with Crohn's Disease.Nutrients · 2021Review
- Growth, puberty, and bone health in children and adolescents with inflammatory bowel disease.BMC pediatrics · 2021Article
- Successful transition from pediatric to adult care in inflammatory bowel disease: what is the key?Intestinal research · 2019Article
- Successful Transition from Pediatric to Adult Care in Inflammatory Bowel Disease: What is the Key?Pediatric gastroenterology, hepatology & nutrition · 2019Review
- Accelerated Step-Up Infliximab Use Is Associated with Sustained Primary Response in Pediatric Crohn's Disease.Digestive diseases and sciences · 2018Article
- Effect of the Baseline Vitamin D Level on Growth Outcome in Pediatric Crohn Disease.Pediatric gastroenterology, hepatology & nutrition · 2017Article
- Childhood Attention-Deficit/Hyperactivity Disorder, Sex, and Obesity: A Longitudinal Population-Based Study.Mayo Clinic proceedings · 2016Article
- Assessing the feasibility of injectable growth-promoting therapy in Crohn's disease.Pilot and feasibility studies · 2016Article
- Two-Year Outcomes After Exclusive Enteral Nutrition Induction Are Superior to Corticosteroids in Pediatric Crohn's Disease Treated Early with Thiopurines.Digestive diseases and sciences · 2015Article
- ADHD, stimulant treatment, and growth: a longitudinal study.Pediatrics · 2014Article
- Endocrine therapy for growth retardation in paediatric inflammatory bowel disease.Paediatric drugs · 2014Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThis study was designed to elucidate the contribution of parental height to the stature of children with inflammatory bowel disease (IBD), who often exhibit growth impairment. Accordingly, we compared patients' final adult heights and target heights based on measured parental heights and examined predictors of final adult height in pediatric IBD patients.
methodsWe prospectively analyzed the growth of 295 patients diagnosed between ages 1 and 18 (211 Crohn's disease [CD], 84 ulcerative colitis [UC]) and their family members (283 mothers, 231 fathers, 55 siblings).
resultsTwenty-two percent had growth impairment (height for age Z-score <-1.64, equivalent to <5th percentile on growth curve) in more than 1 measurement since diagnosis; most growth-impaired patients had CD (88% CD versus 12% UC). Parents of the growth-impaired group had lower mean height Z-scores compared to parents of nongrowth-impaired patients (-0.67 versus 0.02 for mothers [P < 0.001]; -0.31 versus 0.22 for fathers [P = 0.002]). For 108 patients who reached adult heights and had available parental heights, the growth-impaired group continued to demonstrate lower adult height Z-scores (-1.38 versus 0.07; P < 0.001). Adult heights were within 1 SD of target heights even for the growth-impaired group. Only 11.3% remained persistently growth-impaired in adulthood. Multivariate regression analysis demonstrated lower parental height and minimum patient height Z-score as significant predictors of lower final adult height in IBD.
conclusionsParental height is a powerful determinant of linear growth even in the presence of chronic inflammation, and should be an integral part of the evaluation of growth in IBD children.
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Registered trials
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