Evidence map›Paper›PMID 20127889›Full record

ReviewDevelopmental psychobiology2010

How the epigenome contributes to the development of psychiatric disorders.

Timothy W Bredy, Yi E Sun, Michael S Kobor

Abstract readReview
In one paragraph

Review in Developmental psychobiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Epigenetic Mechanisms Within the Cingulate Cortex Regulate Innate Anxiety-Like Behavior.The international journal of neuropsychopharmacology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Epigenetic treatments for cognitive impairments.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy W BredyQueensland Brain Institute, University of Queensland, Brisbane, QC 4072, Australia. tbredy@uq.edu.au
Yi E Sun
Michael S Kobor

Funding

Epigenetic Gene Regulation in Morphin AddictionR03DA022262 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUN, YI EVE · 2006 to 2007
$288k
Common Epigenetic Mechanisms in Cocaine Addiction and Conditioned FearK99DA026503 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BREDY, TIMOTHY W · 2009 to 2009
$151k
CIHRNIDA NIH HHS 1K99 DA026503-01NIDA NIH HHS 1R03 DA022262-01NIDA NIH HHS K99 DA026503NIDA NIH HHS R03 DA022262
6 · The paper itself

Abstract

Epigenetics commonly refers to the developmental process by which cellular traits are established and inherited without a change in DNA sequence. These mechanisms of cellular memory also orchestrate gene expression in the adult brain and recent evidence suggests that the "epigenome" represents a critical interface between environmental signals, activation, repression and maintenance of genomic responses, and persistent behavior. We here review the current state of knowledge regarding the contribution of the epigenome toward the development of psychiatric disorders.

Indexed as

DNA MethylationEpigenesis, GeneticGene ExpressionGenomic ImprintingHistonesHumansMental DisordersHistones

Identifiers

PMID20127889
PMCPMC2946415

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.