ReviewReviews in medical virology2010
Newly identified human rhinoviruses: molecular methods heat up the cold viruses.
Review in Reviews in medical virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Virus detection and its association with symptoms during influenza-like illness in a sample of healthy adults enrolled in a randomised controlled vaccine trial.Influenza and other respiratory viruses · 2013Trial
- Review
- Epidemiology of the Rhinovirus (RV) in African and Southeast Asian Children: A Case-Control Pneumonia Etiology Study.Viruses · 2021Article
- Genotypic diversity, circulation patterns and co-detections among rhinoviruses in Queensland, 2001.Access microbiology · 2020Article
- Transmission of rhinovirus in the Utah BIG-LoVE families: Consequences of age and household structure.PloS one · 2018Article
- Comparative Viral Sampling in the Sinonasal Passages; Different Viruses at Different Sites.Frontiers in cellular and infection microbiology · 2018Article
- Rhinovirus Viremia in Patients Hospitalized With Community-Acquired Pneumonia.The Journal of infectious diseases · 2017Article
- Association of Different Human Rhinovirus Species with Asthma in Children: A Preliminary Study.Chinese medical journal · 2016Article
- Rhinoviruses and Their Receptors: Implications for Allergic Disease.Current allergy and asthma reports · 2016Review
- Toward antiviral therapy/prophylaxis for rhinovirus-induced exacerbations of chronic obstructive pulmonary disease: challenges, opportunities, and strategies.Reviews in medical virology · 2016Review
- Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil.Journal of medical virology · 2016Article
- Genetic diversity of human rhinoviruses in Cambodia during a three-year period reveals novel genetic types.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015Article
- Molecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons.Epidemiology and infection · 2015Article
- Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Pathophysiology of Clinical Symptoms in Acute Viral Respiratory Tract Infections.Advances in experimental medicine and biology · 2015Review
- Molecular epidemiology of human rhinovirus in children with acute respiratory diseases in Chongqing, China.Scientific reports · 2014Article
- Improved molecular typing assay for rhinovirus species A, B, and C.Journal of clinical microbiology · 2014Article
- Interferon lambda 1-3 expression in infants hospitalized for RSV or HRV associated bronchiolitis.The Journal of infection · 2014Article
- The significance of rhinovirus detection in hospitalized children: clinical, epidemiological and virological features.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2013Article
- Respiratory infections in Eñepa Amerindians are related to malnutrition and Streptococcus pneumoniae carriage.The Journal of infection · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human rhinovirus (HRV) infections cause at least 70% of virus-related wheezing exacerbations and cold and flu-like illnesses. They are associated with otitis media, sinusitis and pneumonia. Annually, the economic impact of HRV infections costs billions in healthcare and lost productivity. Since 1987, 100 officially recognised HRV serotypes reside in two genetically distinct species; HRV A and HRV B, within the genus Enterovirus, family Picornaviridae. Sequencing of their approximately 7kb genomes was finalised in 2009. Since 1999, many globally circulating, molecularly-defined 'strains', perhaps equivalent to novel serotypes, have been discovered but remain uncharacterised. Many of these currently unculturable strains have been assigned to a proposed new species, HRV C although confusion exists over the membership of the species. There has not been sufficient sampling to ensure the identification of all strains and no consensus criteria exist to define whether clinical HRV detections are best described as a distinct strain or a closely related variant of a previously identified strain (or serotype). We cannot yet robustly identify patterns in the circulation of newly identified HRVs (niHRVs) or the full range of associated illnesses and more data are required. Many questions arise from this new found diversity: what drives the development of so many distinct viruses compared to other species of RNA viruses? What role does recombination play in generating this diversity? Are there species- or strain-specific circulation patterns and clinical outcomes? Are divergent strains sensitive to existing capsid-binding antivirals? This update reviews the findings that trigger these and other questions arising during the current cycle of intense rhinovirus discovery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.