ArticleInternational archives of occupational and environmental health2010
New-onset adult asthma in relation to damp and moldy workplaces.
Article in International archives of occupational and environmental health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Residential dampness and molds and the risk of developing asthma: a systematic review and meta-analysis.PloS one · 2012Pooled it
- Implementing a complex innovation into workplace operations: The case of work ability support for indoor environment-associated health complaints.Work (Reading, Mass.) · 2026Article
- AWMF mold guideline "Medical clinical diagnostics for indoor mold exposure" - Update 2023 AWMF Register No. 161/001.Allergologie select · 2024Article
- Insights into uncovered public health risks. The case of asthma attacks among archival workers: a cross-sectional study.Frontiers in public health · 2024Article
- Research on Thermal Insulation Performance and Impact on Indoor Air Quality of Cellulose-Based Thermal Insulation Materials.Materials (Basel, Switzerland) · 2023Article
- Season, Vegetation Proximity and Building Age Shape the Indoor Fungal Communities' Composition at City-Scale.Journal of fungi (Basel, Switzerland) · 2022Article
- Changes in Reported Symptoms Attributed to Office Environments in Sweden between 1995 and 2020.International journal of environmental research and public health · 2022Article
- Transcriptomic Profiling of Adult-Onset Asthma Related to Damp and Moldy Buildings and Idiopathic Environmental Intolerance.International journal of molecular sciences · 2021Article
- Influence of TiOMaterials (Basel, Switzerland) · 2021Article
- Indoor mould exposure, asthma and rhinitis: findings from systematic reviews and recent longitudinal studies.European respiratory review : an official journal of the European Respiratory Society · 2018Review
- Association between Four-Level Categorisation of Indoor Exposure and Perceived Indoor Air Quality.International journal of environmental research and public health · 2018Article
- Association Between Sensitization to Mold and Impaired Pulmonary Function in Children With Asthma.Allergy, asthma & immunology research · 2017Article
- Article
- Asthma related to workplace dampness and impaired work ability.International archives of occupational and environmental health · 2014Article
- Airborne bacterial communities in residences: similarities and differences with fungi.PloS one · 2014Article
- Dispersal in microbes: fungi in indoor air are dominated by outdoor air and show dispersal limitation at short distances.The ISME journal · 2013Article
- Article
- A review of the mechanism of injury and treatment approaches for illness resulting from exposure to water-damaged buildings, mold, and mycotoxins.TheScientificWorldJournal · 2013Review
- Prolonged exposure to damp and moldy workplaces and new-onset asthma.International archives of occupational and environmental health · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDamp and moldy indoor environments aggravate pre-existing asthma. Recent meta-analyses suggest that exposure to such environments may also induce new-onset asthma. We assessed the probability of molds being the cause of asthma in a patient series examined because of respiratory symptoms in relation to workplace dampness and molds.
methodsAltogether 694 such patients had been clinically assessed between 1995 and 2004. According to their histories, they had all been exposed to molds at work and had suffered from work-related lower respiratory symptoms. The investigations had included specific inhalation challenge (SIC) tests with mold extracts and serial peak expiratory flow (PEF) recordings. Using internationally recommended diagnostic criteria for occupational asthma (OA), we categorized the patients into three groups: probable, possible, and unlikely OA (156, 45, and 475 patients, respectively). The clinical details of 258 patients were analyzed, and their levels of microbial exposure were evaluated.
resultsThe agreement between the serial PEF recordings and SIC tests (both being either positive or negative) was 56%. In the group of probable OA, mold sensitization was found in 20%. The level of exposure and sensitization to molds was associated with probable OA. At 6 months, the follow-up examinations of 136 patients with probable OA showed that the symptoms were persistent, and no improvement in spirometry was noted despite adequate treatment. Only 58% of the patients had returned to work.
conclusionsExposure to damp and moldy workplaces can induce new-onset adult asthma. IgE mediation is a rare mechanism, whereas other mechanisms are unknown.
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