The subchondral bone: a new frontier in articular cartilage repair.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Subchondral drilling for articular cartilage repair: a systematic review of translational research.Disease models & mechanisms · 2018
   Pooled it
2. Biological aspects of early osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2012
   Pooled it
3. Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis.Cell proliferation · 2026
   Article
4. Insights of cartilage imaging in cartilage regeneration.World journal of orthopedics · 2025
   Review
5. Regenerative Variability of Human Juvenile Chondrocyte Sheets From Different Cell Donors in an Athymic Rat Knee Chondral Defect Model.Cartilage · 2024
   Article
6. "Bone-SASP" in Skeletal Aging.Calcified tissue international · 2023
   Review
7. Long-term Assessment of Subchondral Bone Changes and Intralesional Bony Overgrowth After Third-Generation Autologous Chondrocyte Implantation: A Retrospective Study.The American journal of sports medicine · 2023
   Article
8. Computed tomography Osteoabsorptiometry: Review of bone density, mechanical strength of material and clinical application.Frontiers in bioengineering and biotechnology · 2023
   Review
9. PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis.Bone research · 2022
   Article
10. miR-17-92 cluster in osteoarthritis: Regulatory roles and clinical utility.Frontiers in genetics · 2022
    Review
11. Chondrogenic differentiation of human bone marrow MSCs in osteochondral implants under kinematic mechanical load is dependent on the underlying osteo component.Frontiers in bioengineering and biotechnology · 2022
    Article
12. In vivo evaluation of additively manufactured multi-layered scaffold for the repair of large osteochondral defects.Bio-design and manufacturing · 2022
    Article
13. Morphological Assessment of MACI Grafts in Patients with Revision Surgery and Total Joint Arthroplasty.Cartilage · 2021
    Article
14. Prior Bone Marrow Stimulation Surgery Influences Outcomes After Cell-Based Cartilage Restoration: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2021
    Review
15. Differences in subchondral trabecular bone microstructure and finite element analysis-based biomechanical properties between osteoporosis and osteoarthritis.Journal of orthopaedic translation · 2020
    Article
16. Third-generation autologous chondrocyte implantation after failed bone marrow stimulation leads to inferior clinical results.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Article
17. Selective laser sintering scaffold with hierarchical architecture and gradient composition for osteochondral repair in rabbits.Biomaterials · 2017
    Article
18. Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone.Annals of the rheumatic diseases · 2016
    Article
19. High level of interleukin-32 gamma in the joint of ankylosing spondylitis is associated with osteoblast differentiation.Arthritis research & therapy · 2015
    Article
20. Large animal models in experimental knee sports surgery: focus on clinical translation.Journal of experimental orthopaedics · 2015
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as