ArticleFrontiers in cellular neuroscience2010
Cerebellar and extracerebellar involvement in mouse eyeblink conditioning: the ACDC model.
Article in Frontiers in cellular neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- The Role of Cerebellar Intrinsic Neuronal Excitability, Synaptic Plasticity, and Perineuronal Nets in Eyeblink Conditioning.Biology · 2024Review
- Impact of enriched environment on motor performance and learning in mice.Scientific reports · 2024Article
- Discrimination training affects stimulus generalization in mice during Pavlovian eyeblink conditioning.Frontiers in behavioral neuroscience · 2024Article
- Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1.Brain : a journal of neurology · 2023Article
- Delay eyeblink conditioning performance and brain-wide c-Fos expression in male and female mice.Open biology · 2023Article
- Purkinje cell dopaminergic inputs to astrocytes regulate cerebellar-dependent behavior.Nature communications · 2023Article
- Role of cerebellum in sleep-dependent memory processes.Frontiers in systems neuroscience · 2023Review
- Cerebellum-dependent associative learning is not impaired in a mouse model of neurofibromatosis type 1.Scientific reports · 2022Article
- Atypical cerebellar functional connectivity at 9 months of age predicts delayed socio-communicative profiles in infants at high and low risk for autism.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning.Journal of visualized experiments : JoVE · 2022Article
- Functional properties of eyelid conditioned responses and involved brain centers.Frontiers in behavioral neuroscience · 2022Review
- Role of the motor cortex in the generation of classically conditioned eyelid and vibrissae responses.Scientific reports · 2021Article
- Macaque monkey trigeminal blink reflex circuits targeting orbicularis oculi motoneurons.The Journal of comparative neurology · 2021Article
- Amygdala central nucleus modulation of cerebellar learning in female rats.Behavioral neuroscience · 2021Article
- Article
- Young Domestic PigsFrontiers in behavioral neuroscience · 2021Article
- Modulatory Effects of Monoamines and Perineuronal Nets on Output of Cerebellar Purkinje Cells.Frontiers in neural circuits · 2021Review
- Intracerebellar cannabinoid administration impairs delay but not trace eyeblink conditioning.Behavioural brain research · 2020Article
- Changes in cerebellar intrinsic neuronal excitability and synaptic plasticity result from eyeblink conditioning.Neurobiology of learning and memory · 2019Review
- A method for combining multiple-units readout of optogenetic control with natural stimulation-evoked eyeblink conditioning in freely-moving mice.Scientific reports · 2019Article
1 more citing papers are in PubMed but not listed here.
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3 authors.
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Abstract
Over the past decade the advent of mouse transgenics has generated new perspectives on the study of cerebellar molecular mechanisms that are essential for eyeblink conditioning. However, it also appears that results from eyeblink conditioning experiments done in mice differ in some aspects from results previously obtained in other mammals. In this review article we will, based on studies using (cell-specific) mouse mutants and region-specific lesions, re-examine the general eyeblink behavior in mice and the neuro-anatomical circuits that might contribute to the different peaks in the conditioned eyeblink trace. We conclude that the learning process in mice has at least two stages: An early stage, which includes short-latency responses that are at least partly controlled by extracerebellar structures such as the amygdala, and a later stage, which is represented by well-timed conditioned responses that are mainly controlled by the pontocerebellar and olivocerebellar systems. We refer to this overall concept as the Amygdala-Cerebellum-Dynamic-Conditioning Model (ACDC model).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.