ArticleJournal of biomedical informatics2011
Hematopoietic cell types: prototype for a revised cell ontology.
Article in Journal of biomedical informatics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- The Cell Ontology in the age of single-cell omics.Scientific data · 2026Article
- A machine learning method for the discovery of minimum marker gene combinations for cell type identification from single-cell RNA sequencing.Genome research · 2021Article
- A Literature-Derived Knowledge Graph Augments the Interpretation of Single Cell RNA-seq Datasets.Genes · 2021Article
- The Minimum Information about a Molecular Interaction CAusal STatement (MI2CAST).Bioinformatics (Oxford, England) · 2021Article
- Ontology-guided segmentation and object identification for developmental mouse lung immunofluorescent images.BMC bioinformatics · 2021Article
- An ontology for representing hematologic malignancies: the cancer cell ontology.BMC bioinformatics · 2019Article
- Cell type discovery using single-cell transcriptomics: implications for ontological representation.Human molecular genetics · 2018Article
- Cell type discovery and representation in the era of high-content single cell phenotyping.BMC bioinformatics · 2017Article
- The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability.Journal of biomedical semantics · 2016Article
- flowCL: ontology-based cell population labelling in flow cytometry.Bioinformatics (Oxford, England) · 2015Article
- Biomedical imaging ontologies: A survey and proposal for future work.Journal of pathology informatics · 2015Article
- Ontology-based representation and analysis of host-Brucella interactions.Journal of biomedical semantics · 2015Article
- Ontology-supported research on vaccine efficacy, safety and integrative biological networks.Expert review of vaccines · 2014Review
- CLO: The cell line ontology.Journal of biomedical semantics · 2014Article
- Protein Ontology: a controlled structured network of protein entities.Nucleic acids research · 2014Article
- Ontology based molecular signatures for immune cell types via gene expression analysis.BMC bioinformatics · 2013Article
- OPPL-Galaxy, a Galaxy tool for enhancing ontology exploitation as part of bioinformatics workflows.Journal of biomedical semantics · 2013Article
- Advances in human B cell phenotypic profiling.Frontiers in immunology · 2012Article
- Cross-product extensions of the Gene Ontology.Journal of biomedical informatics · 2011Article
- Ontologies for clinical and translational research: Introduction.Journal of biomedical informatics · 2011Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
The Cell Ontology (CL) aims for the representation of in vivo and in vitro cell types from all of biology. The CL is a candidate reference ontology of the OBO Foundry and requires extensive revision to bring it up to current standards for biomedical ontologies, both in its structure and its coverage of various subfields of biology. We have now addressed the specific content of one area of the CL, the section of the ontology dealing with hematopoietic cells. This section has been extensively revised to improve its content and eliminate multiple inheritance in the asserted hierarchy, and the groundwork has been laid for structuring the hematopoietic cell type terms as cross-products incorporating logical definitions built from relationships to external ontologies, such as the Protein Ontology and the Gene Ontology. The methods and improvements to the CL in this area represent a paradigm for improvement of the entire ontology over time.
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Registered trials
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