Evidence map›Paper›PMID 20123127›Full record

ArticleMethods (San Diego, Calif.)2010

Preparation of a highly active cell-free translation system from immature Xenopus laevis oocytes.

Catherine A Pratt, Kimberly L Mowry

Abstract read
In one paragraph

Article in Methods (San Diego, Calif.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Catherine A PrattDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912, USA.
Kimberly L Mowry
Brown University · US

Funding

RNA Localization in Xenopus OocytesR01GM071049 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 2005 to 2018
$4.2M
NIGMS NIH HHS R01 GM071049NIGMS NIH HHS R01GM071049
6 · The paper itself

Abstract

Understanding mechanisms of post-transcriptional control of gene expression has come under much scrutiny in recent years. A key question in this field is how the translation of specific mRNAs is activated or repressed both spatially and temporally in a given cell. In oocytes of the frog Xenopus laevis a number of mRNAs are localized early in oogenesis and subsequently translated at later stages. We have developed a highly active cell-free translation system from oocytes in the early stages of oogenesis that is applicable to the study of translation and translational control of both endogenous and exogenous mRNAs.

Indexed as

AnimalsCell-Free SystemCytological TechniquesGenes, ReporterLuciferasesModels, BiologicalModels, GeneticOocytesProtein BiosynthesisRNA, MessengerTime FactorsXenopus laevisLuciferasesRNA, Messenger

Identifiers

PMID20123127
PMCPMC2868112
OpenAlexW2007502779

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.