Evidence map›Paper›PMID 20122312›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2010

Coagulation profiling of random-source cats.

Elizabeth McGeehan, Karen Wielgus, Lee Cera, Farshid Azarafrooz, Rose Buesing, Jean Dubach, Jawed Fareed

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth McGeehanDepartment of Comparative Medicine, Loyola University Medical Center, Maywood, Illinois, USA. emcgeehan@lumc.edu
Karen Wielgus
Lee Cera
Farshid Azarafrooz
Rose Buesing
Jean Dubach
Jawed Fareed

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chemistry and hemostatic parameters of class B vendor cats (Felis catus) can show wide levels of variation, possibly because of initial health status. We compared prothrombin time, partial thromboplastin time, common pathway assay and thrombin time between Class B vendor cats (n = 30) and a control group of healthy cats (n = 16). The antiprotease activities of antiXa, antiIIa, heparin cofactor II, and antithrombin were measured also. Plasma samples from citrated blood were analyzed by using standard clotting assays and commercially available chromogenic substrate assays. Tests for homogeneity of variances and 1-way ANOVA were used to test for significant differences between groups. Results of ANOVA were highly significant between groups for heparin cofactor II and Heptest activity levels. Variances were significantly different between groups for prothrombin time; therefore, an ANOVA was not done. These studies suggest that the class B cats exhibited sufficiently wide variations in their coagulation parameters that they may not be optimal subjects for vascular or cardiovascular research.

Indexed as

Disease Models, AnimalAnalysis of VarianceAnimalsAnimals, LaboratoryBlood Coagulation TestsCase-Control StudiesCatsFemaleMalePartial Thromboplastin TimeProtease InhibitorsProthrombin TimeThrombin TimeProtease Inhibitors

Identifiers

PMID20122312
PMCPMC2824963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.