Evidence map›Paper›PMID 20121112›Full record

ArticleJournal of medicinal chemistry2010

Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm?

Peter Oelschlaeger, Ni Ai, Kevin T Duprez, William J Welsh, Jeffrey H Toney

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Synergistic Effects of Amikacin With Imipenem and Ciprofloxacin Against Multidrug-Resistance UropathogenicThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter OelschlaegerChemistry Department and Center for Macromolecular Modeling and Materials Design, California State Polytechnic University, Pomona, California, USA. oelschlaeger@csupomona.edu
Ni Ai
Kevin T Duprez
William J Welsh
Jeffrey H Toney

Funding

Shape Signatures, an Open Resource for Drug DiscoveryR21GM081394 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI WELSH, WILLIAM J · 2007 to 2008
$429k
Howard Hughes Medical InstituteNIGMS NIH HHS R21 GM081394NIGMS NIH HHS R21-GM081394
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DesignAlgorithmsAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamase Inhibitorsbeta-LactamasesCarbapenemsCrystallography, X-RayDatabases, FactualDrug Resistance, Multiple, BacterialKlebsiella pneumoniaeMetalloproteinsModels, MolecularMutationProtein ConformationSubstrate SpecificityAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamase Inhibitorsbeta-Lactamasescarbapenemasecarbapenemase-2, Klebsiella pneumoniaeCarbapenemsMetalloproteins

Identifiers

PMID20121112
PMCPMC2855403

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.