Evidence map›Paper›PMID 20119672›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2010

Additional pain relieving effect of intraoperative periarticular injections after simultaneous bilateral TKA: a randomized, controlled study.

In Jun Koh, Yeon Gwi Kang, Chong Bum Chang, Sae Kwang Kwon, Eun Seok Seo, Sang Cheol Seong, Tae Kyun Kim

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03249662 (Efficacy of Pain Management in Different Concentrations of Bupivacaine in Periarticular Injection and Plasma Concentrations of Bupivacaine in Patients Undergoing Bilateral Knee Arthroplasty), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03249662 nacompletednot on this mapstarted 2017, after this paper: background citation

Efficacy of Pain Management in Different Concentrations of Bupivacaine in Periarticular Injection and Plasma Concentrations of Bupivacaine in Patients Undergoing Bilateral Knee Arthroplasty

TypeinterventionalSponsorMahidol UniversityRan2017 to 2020Enrolled60ConditionsBilateral Total Knee ArthroplastyArmsbupivacaine 200 mg, bupivacaine 100 mg
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Periarticular multimodal drug injection in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014
    Pooled it
  5. Trial
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  10. Effects of dexamethasone on local infiltration analgesia in total knee arthroplasty: a randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014
    Trial
  11. Multimodal analgesia for arthroscopic rotator cuff repair: a randomized, placebo-controlled, double-blind trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2014
    Trial
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  15. Does ramosetron reduce postoperative emesis and pain after TKA?Clinical orthopaedics and related research · 2012
    Trial
  16. Article
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  18. Article
  19. Optimizing Intraoperative Blood Management for One-Stage Bilateral Total Knee Arthroplasty.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

In Jun KohJoint Reconstruction Center, Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Korea.
Yeon Gwi Kang
Chong Bum Chang
Sae Kwang Kwon
Eun Seok Seo
Sang Cheol Seong
Tae Kyun Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors investigated the clinical value of intraoperative periarticular multimodal drug injections (PMDI) in patients on continuous epidural analgesia after simultaneous bilateral TKAs. In 55 patients scheduled to undergo simultaneous bilateral TKAs, one knee was randomly assigned to the PMDI group for which intraoperative periarticular injections were administered and the other knee was assigned to the No-PMDI group for which the injections were not done. These two groups were compared for pain level (during the operation night and on postoperative days (POD) 1, 4, and 7), functional recovery (ability to perform straight leg raising on POD 1 and maximum flexion on POD 7), patient satisfaction (POD 7), and the incidence of wound complications. The PMDI group showed a lower pain level during the operation night and on POD 1 than the No-PMDI group, but no differences in pain levels were observed between the groups on POD 4 or 7. Furthermore, no significant group differences were found in terms of functional recovery, patient satisfaction. No wound complication has been occurred in the PMDI group. This study demonstrates that PMDI provides additional pain relief limited to the immediate postoperative period but does not improve pain relief after POD 1, patient satisfaction and functional recovery.

Indexed as

AgedAmidesAnesthetics, LocalArthroplasty, Replacement, KneeDrug CombinationsFemaleHumansInjectionsIntraoperative CareKetorolacMaleMiddle AgedMorphinePain MeasurementPatient SatisfactionPostoperative PainAmidesAnesthetics, LocalDrug CombinationsKetorolacMorphineRopivacaine

Identifiers

PMID20119672

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.