ArticleHFSP journal2009
Traction forces during collective cell motion.
Article in HFSP journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 56 citations in OpenAlex.
- Silver Nanoparticles at Low Concentrations Embedded in ECM Promote Endothelial Monolayer Formation and Cell Migration.International journal of molecular sciences · 2025Article
- 3D Traction Force Microscopy in Biological Gels: From Single Cells to Multicellular Spheroids.Annual review of biomedical engineering · 2024Review
- MAP4K4 regulates forces at cell-cell and cell-matrix adhesions to promote collective cell migration.Life science alliance · 2023Article
- Bioelectronic microfluidic wound healing: a platform for investigating direct current stimulation of injured cell collectives.Lab on a chip · 2023Article
- Wound Healing from an Actin Cytoskeletal Perspective.Cold Spring Harbor perspectives in biology · 2022Review
- P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers.Cell adhesion & migration · 2021Article
- The role of single cell mechanical behavior and polarity in driving collective cell migration.Nature physics · 2020Article
- A mechanical toy model linking cell-substrate adhesion to multiple cellular migratory responses.Journal of biological physics · 2019Article
- The Interplay Between Cell-Cell and Cell-Matrix Forces Regulates Cell Migration Dynamics.Biophysical journal · 2019Article
- Microfabricated tissues for investigating traction forces involved in cell migration and tissue morphogenesis.Cellular and molecular life sciences : CMLS · 2017Review
- Onset of nonlinearity in a stochastic model for auto-chemotactic advancing epithelia.Scientific reports · 2016Article
- P-cadherin-mediated Rho GTPase regulation during collective cell migration.Small GTPases · 2016Review
- Inference of Internal Stress in a Cell Monolayer.Biophysical journal · 2016Article
- Modeling and analysis of collective cell migration in an in vivo three-dimensional environment.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration.Biophysical journal · 2015Article
- Regulation of epithelial cell organization by tuning cell-substrate adhesion.Integrative biology : quantitative biosciences from nano to macro · 2015Article
- The mechanotransduction machinery at work at adherens junctions.Integrative biology : quantitative biosciences from nano to macro · 2015Review
- Mechanisms of endothelial cell migration.Cellular and molecular life sciences : CMLS · 2014Review
- Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Propagating waves of directionality and coordination orchestrate collective cell migration.PLoS computational biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Collective motion of cell cultures is a process of great interest, as it occurs during morphogenesis, wound healing, and tumor metastasis. During these processes cell cultures move due to the traction forces induced by the individual cells on the surrounding matrix. A recent study [Trepat, et al. (2009). Nat. Phys. 5, 426-430] measured for the first time the traction forces driving collective cell migration and found that they arise throughout the cell culture. The leading 5-10 rows of cell do play a major role in directing the motion of the rest of the culture by having a distinct outwards traction. Fluctuations in the traction forces are an order of magnitude larger than the resultant directional traction at the culture edge and, furthermore, have an exponential distribution. Such exponential distributions are observed for the sizes of adhesion domains within cells, the traction forces produced by single cells, and even in nonbiological nonequilibrium systems, such as sheared granular materials. We discuss these observations and their implications for our understanding of cellular flows within a continuous culture.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.