ArticleNature neuroscience2010
Dichotomy of functional organization in the mouse auditory cortex.
Article in Nature neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.
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Who cites it
137 citing papers in PubMed.
- Stimulus-specific suppression preserves information in auditory short-term memory.Proceedings of the National Academy of Sciences of the United States of America · 2011Trial
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- Layer 6 corticothalamic neurons show diverse and dynamic responses that support a role in cortical gain control in noisy environments.bioRxiv : the preprint server for biology · 2026Article
- A Protocol for Microprism-Based Two-Photon Imaging Of The Lateral Cortex In The Mouse Inferior Colliculus.Current protocols · 2026Article
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- Rapid rebalancing of co-tuned ensemble activity in the auditory cortex.bioRxiv : the preprint server for biology · 2025Article
- Patchy harmonic functional connectivity of the mouse auditory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Intermingled representation of oral cavity in mouse trigeminal ganglion.Scientific reports · 2025Article
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- Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.Frontiers in pharmacology · 2025Article
- Differential Encoding of Two-Tone Harmonics in the Male and Female Mouse Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Plateau depolarizations in spontaneously active neurons detected by calcium or voltage imaging.Scientific reports · 2024Article
- Topography and Ensemble Activity in the Auditory Cortex of a Mouse Model of Fragile X Syndrome.eNeuro · 2024Article
- Auditory Corticofugal Neurons Transmit Auditory and Non-auditory Information During Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Fractured columnar small-world functional network organization in volumes of L2/3 of mouse auditory cortex.PNAS nexus · 2024Article
- Predictive Mouse Ultrasonic Vocalization Sequences: Uncovering Behavioral Significance, Auditory Cortex Neuronal Preferences, and Social-Experience-Driven Plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
77 more citing papers are in PubMed but not listed here.
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3 authors.
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Abstract
The sensory areas of the cerebral cortex possess multiple topographic representations of sensory dimensions. The gradient of frequency selectivity (tonotopy) is the dominant organizational feature in the primary auditory cortex, whereas other feature-based organizations are less well established. We probed the topographic organization of the mouse auditory cortex at the single-cell level using in vivo two-photon Ca(2+) imaging. Tonotopy was present on a large scale but was fractured on a fine scale. Intensity tuning, which is important in level-invariant representation, was observed in individual cells, but was not topographically organized. The presence or near absence of putative subthreshold responses revealed a dichotomy in topographic organization. Inclusion of subthreshold responses revealed a topographic clustering of neurons with similar response properties, whereas such clustering was absent in supra-threshold responses. This dichotomy indicates that groups of nearby neurons with locally shared inputs can perform independent parallel computations in the auditory cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.