Evidence map›Paper›PMID 20118252›Full record

ArticleJournal of bacteriology2010

The physiological stimulus for the BarA sensor kinase.

Ricardo Gonzalez Chavez, Adrian F Alvarez, Tony Romeo, Dimitris Georgellis

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 151 citations in OpenAlex.

  1. Article
  2. Review
  3. AProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Current understandings of colibactin regulation.Microbiology (Reading, England) · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Infection and immunity · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Three Ribosomal Operons ofFrontiers in microbiology · 2021
    Article
  18. Identification of Z nucleotides as an ancient signal for two-component system activation in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  19. Review
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ricardo Gonzalez ChavezDepartamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Adrian F Alvarez
Tony Romeo
Dimitris Georgellis
Universidad Nacional Autónoma de México · MXUniversity of Florida · US

Funding

Mechanism of CsrA-mediated global regulationR01GM059969 · NIGMS · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI BABITZKE, PAUL L, ROMEO, TONY · 1999 to 2021
$7.6M
NIGMS NIH HHS R01 GM059969
6 · The paper itself

Abstract

The two-component signal transduction system (TCS) BarA/UvrY activates transcription of CsrB and CsrC noncoding RNAs, which act by sequestering the RNA-binding global regulatory protein CsrA. Here, we show that the metabolic end products formate and acetate provide a physiological stimulus for this TCS and thus link posttranscriptional regulation by the Csr system to the metabolic state of the cell.

Indexed as

Gene Expression Regulation, BacterialSignal TransductionAcetic AcidEscherichia coliEscherichia coli ProteinsFormatesMembrane ProteinsPhosphotransferasesAcetic AcidbarA protein, E coliEscherichia coli ProteinsFormatesformic acidMembrane ProteinsPhosphotransferases

Identifiers

PMID20118252
PMCPMC2838055
OpenAlexW2043472647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.